Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Protein skinhead-1
Ligand
BDBM93743
Substrate
n/a
IC50
11200±n/a nM
Citation
PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
Inhibitor
Name:
BDBM93743
Synonyms:
3-[(4-chlorobenzyl)sulfanyl]-1-phenyl-1H-1,2,4-triazole | 3-[(4-chlorobenzyl)thio]-1-phenyl-1,2,4-triazole | 3-[(4-chlorophenyl)methylsulfanyl]-1-phenyl-1,2,4-triazole | 3-[(4-chlorophenyl)methylthio]-1-phenyl-1,2,4-triazole | MLS000550104 | SMR000115139 | cid_1778827
Type:
Small organic molecule
Emp. Form.:
C15H12ClN3S
Mol. Mass.:
301.794
SMILES:
Clc1ccc(CSc2ncn(n2)-c2ccccc2)cc1
Structure:
