Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM48206
Substrate
n/a
IC50
5910±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM48206
Synonyms:
2-(2-pyridinyl)-1H-benzo[f]benzimidazole | 2-(2-pyridyl)-1H-benzo[f]benzimidazole | 2-Pyridin-2-yl-1H-naphtho[2,3-d]imidazole | 2-pyridin-2-yl-1H-benzo[f]benzimidazole | MLS000122414 | SMR000119845 | cid_1084688
Type:
Small organic molecule
Emp. Form.:
C16H11N3
Mol. Mass.:
245.2786
SMILES:
c1ccc(nc1)-c1nc2cc3ccccc3cc2[nH]1
Structure:
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