Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM56718
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM56718
Synonyms:
MLS001018774 | N-[4-(difluoromethylsulfanyl)phenyl]-2-fluorobenzamide | N-[4-(difluoromethylthio)phenyl]-2-fluoro-benzamide | N-[4-(difluoromethylthio)phenyl]-2-fluorobenzamide | N-[4-[bis(fluoranyl)methylsulfanyl]phenyl]-2-fluoranyl-benzamide | SMR000363283 | cid_2308454
Type:
Small organic molecule
Emp. Form.:
C14H10F3NOS
Mol. Mass.:
297.296
SMILES:
FC(F)Sc1ccc(NC(=O)c2ccccc2F)cc1
Structure:
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