Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM47960
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM47960
Synonyms:
MLS000732969 | N-[(2-biphenyl-4-yl-5-methyl-1,3-oxazol-4-yl)methyl]-N-methyltetrahydrofuran-3-amine | N-methyl-N-[[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]methyl]oxolan-3-amine | N-methyl-N-[[5-methyl-2-(4-phenylphenyl)-4-oxazolyl]methyl]-3-oxolanamine | SMR000316222 | cid_16191300 | methyl-[[5-methyl-2-(4-phenylphenyl)oxazol-4-yl]methyl]-tetrahydrofuran-3-yl-amine
Type:
Small organic molecule
Emp. Form.:
C22H24N2O2
Mol. Mass.:
348.4382
SMILES:
CN(Cc1nc(oc1C)-c1ccc(cc1)-c1ccccc1)C1CCOC1
Structure:
Search PDB for entries with ligand similarity: