Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM49562
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM49562
Synonyms:
(E)-3-(3,4-difluoroanilino)-1-(2-thienyl)prop-2-en-1-one | (E)-3-(3,4-difluoroanilino)-1-thiophen-2-yl-2-propen-1-one | (E)-3-(3,4-difluoroanilino)-1-thiophen-2-ylprop-2-en-1-one | (E)-3-[[3,4-bis(fluoranyl)phenyl]amino]-1-thiophen-2-yl-prop-2-en-1-one | 3-[(3,4-difluorophenyl)amino]-1-(2-thienyl)-2-propen-1-one | MLS000581375 | SMR000199995 | cid_2210533
Type:
Small organic molecule
Emp. Form.:
C13H9F2NOS
Mol. Mass.:
265.278
SMILES:
Fc1ccc(cc1F)N=CCC(=O)c1cccs1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: