Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95029
Substrate
n/a
IC50
4770±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95029
Synonyms:
2-[4-(2-methyl-4-quinolinyl)-1-piperazinyl]-4-(4-nitrophenyl)thiazole | 2-[4-(2-methyl-4-quinolyl)piperazino]-4-(4-nitrophenyl)thiazole | 2-[4-(2-methylquinolin-4-yl)piperazin-1-yl]-4-(4-nitrophenyl)-1,3-thiazole | 2-methyl-4-{4-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]piperazin-1-yl}quinoline | MLS000728914 | SMR000307192 | cid_1520389
Type:
Small organic molecule
Emp. Form.:
C23H21N5O2S
Mol. Mass.:
431.51
SMILES:
Cc1cc(N2CCN(CC2)c2nc(cs2)-c2ccc(cc2)[N+]([O-])=O)c2ccccc2n1
Structure:
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