Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95049
Substrate
n/a
IC50
7120±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95049
Synonyms:
(3-Morpholin-4-yl-propyl)-(2-m-tolyl-quinazolin-4-yl)-amine | 2-(3-methylphenyl)-N-(3-morpholin-4-ylpropyl)quinazolin-4-amine | 2-(3-methylphenyl)-N-[3-(4-morpholinyl)propyl]-4-quinazolinamine | 3-morpholinopropyl-[2-(m-tolyl)quinazolin-4-yl]amine | MLS000527359 | SMR000117833 | cid_1566769
Type:
Small organic molecule
Emp. Form.:
C22H26N4O
Mol. Mass.:
362.468
SMILES:
Cc1cccc(c1)-c1nc(NCCCN2CCOCC2)c2ccccc2n1
Structure:
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