Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95193
Substrate
n/a
IC50
16300±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM95193
Synonyms:
4-methyl-N-[4-[(3-naphthalen-2-ylimidazo[1,2-a]pyrazin-8-yl)amino]phenyl]benzenesulfonamide | 4-methyl-N-[4-[[3-(2-naphthalenyl)-8-imidazo[1,2-a]pyrazinyl]amino]phenyl]benzenesulfonamide | 4-methyl-N-[4-[[3-(2-naphthyl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]benzenesulfonamide | MLS003123239 | SMR001454237 | cid_46942474
Type:
Small organic molecule
Emp. Form.:
C29H23N5O2S
Mol. Mass.:
505.59
SMILES:
Cc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2nccn3c(cnc23)-c2ccc3ccccc3c2)cc1
Structure:
