Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 5
Ligand
BDBM84339
Substrate
n/a
EC50
19.6±n/a nM
Citation
 PubChem, PC Counter screen for HTS for Beta-2AR agonists with FAP-tagged human CCR5 with Powderset2 PubChem Bioassay (2012)[AID] 
Target
Name:
C-C chemokine receptor type 5
Synonyms:
C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor
Type:
Enzyme
Mol. Mass.:
40540.21
Organism:
Homo sapiens (Human)
Description:
P51681
Residue:
352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
  
Inhibitor
Name:
BDBM84339
Synonyms:
MLS001167316 | N-[4-[2-(2-pyridin-3-yl-1,3-thiazol-4-yl)ethylsulfamoyl]phenyl]acetamide | N-[4-[2-(2-pyridin-3-yl-1,3-thiazol-4-yl)ethylsulfamoyl]phenyl]ethanamide | N-[4-[2-[2-(3-pyridinyl)-4-thiazolyl]ethylsulfamoyl]phenyl]acetamide | N-[4-[2-[2-(3-pyridyl)thiazol-4-yl]ethylsulfamoyl]phenyl]acetamide | SMR000806089 | cid_16832456
Type:
Small organic molecule
Emp. Form.:
C18H18N4O3S2
Mol. Mass.:
402.491
SMILES:
CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCc1csc(n1)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: