Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM68012
Substrate
n/a
IC50
13848±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM68012
Synonyms:
2-benzoyl-3-phenyl-1,4-naphthoquinone | 2-benzoyl-3-phenylnaphthalene-1,4-dione | 2-benzoyl-3-phenylnaphthoquinone | 2-phenyl-3-(phenylcarbonyl)naphthalene-1,4-dione | MLS000584172 | SMR000203335 | cid_3841172
Type:
Small organic molecule
Emp. Form.:
C23H14O3
Mol. Mass.:
338.3555
SMILES:
O=C(C1=C(C(=O)c2ccccc2C1=O)c1ccccc1)c1ccccc1 |t:2|
Structure:
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