Reaction Details
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Report a problem with these dataTarget
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95399
Substrate
n/a
IC50
53600±n/a nM
Citation
PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
Inhibitor
Name:
BDBM95399
Synonyms:
1'H-spiro[cyclopentane-1,2'-quinazoline]-4'(3'H)-thione | 4-spiro[1,3-dihydroquinazoline-2,1'-cyclopentane]thione | MLS000730176 | SMR000308452 | cid_686361 | spiro[1,3-dihydroquinazoline-2,1'-cyclopentane]-4-thione
Type:
Small organic molecule
Emp. Form.:
C12H14N2S
Mol. Mass.:
218.318
SMILES:
S=C1NC2(CCCC2)Nc2ccccc12
Structure:
