Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95044
Substrate
n/a
IC50
9530±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95044
Synonyms:
2-N-(2-methoxyethyl)-4-N-[[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl]thieno[3,2-d]pyrimidine-2,4-diamine | 2-methoxyethyl-[4-[[3-(4-methoxyphenyl)isoxazol-5-yl]methylamino]thieno[3,2-d]pyrimidin-2-yl]amine | MLS003122932 | N2-(2-methoxyethyl)-N4-[[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl]thieno[3,2-d]pyrimidine-2,4-diamine | N2-(2-methoxyethyl)-N4-[[3-(4-methoxyphenyl)-5-isoxazolyl]methyl]thieno[3,2-d]pyrimidine-2,4-diamine | SMR001277939 | cid_49792522
Type:
Small organic molecule
Emp. Form.:
C20H21N5O3S
Mol. Mass.:
411.477
SMILES:
COCCNc1nc(NCc2cc(no2)-c2ccc(OC)cc2)c2sccc2n1
Structure:
Search PDB for entries with ligand similarity: