Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94902
Substrate
n/a
IC50
12300±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94902
Synonyms:
2-N-(cyclopropylmethyl)-4-N-[(2,3-dimethoxyphenyl)methyl]thieno[3,2-d]pyrimidine-2,4-diamine | MLS003122959 | N2-(cyclopropylmethyl)-N4-[(2,3-dimethoxyphenyl)methyl]thieno[3,2-d]pyrimidine-2,4-diamine | SMR001277993 | cid_49792581 | cyclopropylmethyl-[4-(o-veratrylamino)thieno[3,2-d]pyrimidin-2-yl]amine
Type:
Small organic molecule
Emp. Form.:
C19H22N4O2S
Mol. Mass.:
370.469
SMILES:
COc1cccc(CNc2nc(NCC3CC3)nc3ccsc23)c1OC
Structure:
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