Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM89995
Substrate
n/a
IC50
>118542±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM89995
Synonyms:
2-anilino-N'-({5-nitro-2-furyl}methylene)acetohydrazide | 2-anilino-N-[(E)-(5-nitro-2-furanyl)methylideneamino]acetamide | 2-anilino-N-[(E)-(5-nitro-2-furyl)methyleneamino]acetamide | 2-anilino-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]acetamide | MLS000545151 | N-[(E)-(5-nitrofuran-2-yl)methylideneamino]-2-phenylazanyl-ethanamide | SMR000164126 | cid_9564693
Type:
Small organic molecule
Emp. Form.:
C13H12N4O4
Mol. Mass.:
288.2588
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)CNc2ccccc2)o1
Structure:
Search PDB for entries with ligand similarity: