Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM87296
Substrate
n/a
IC50
>118441±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM87296
Synonyms:
2-(3-nitroanilino)-N-[(E)-(5-nitro-2-furanyl)methylideneamino]acetamide | 2-(3-nitroanilino)-N-[(E)-(5-nitro-2-furyl)methyleneamino]acetamide | 2-(3-nitroanilino)-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]acetamide | 2-{3-nitroanilino}-N'-({5-nitro-2-furyl}methylene)acetohydrazide | MLS000702290 | N-[(E)-(5-nitrofuran-2-yl)methylideneamino]-2-[(3-nitrophenyl)amino]ethanamide | SMR000224514 | cid_6872741
Type:
Small organic molecule
Emp. Form.:
C13H11N5O6
Mol. Mass.:
333.2563
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)CNc2cccc(c2)[N+]([O-])=O)o1
Structure:
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