Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM96310
Substrate
n/a
IC50
10558±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM96310
Synonyms:
4-methylbenzenesulfonic acid [4-[(E)-[[2-(4-chlorophenoxy)-1-oxoethyl]hydrazinylidene]methyl]-2-methoxyphenyl] ester | 4-methylbenzenesulfonic acid [4-[(E)-[[2-(4-chlorophenoxy)acetyl]hydrazono]methyl]-2-methoxy-phenyl] ester | 4-{2-[(4-chlorophenoxy)acetyl]carbohydrazonoyl}-2-methoxyphenyl 4-methylbenzenesulfonate | MLS000324668 | SMR000163796 | [4-[(E)-[2-(4-chloranylphenoxy)ethanoylhydrazinylidene]methyl]-2-methoxy-phenyl] 4-methylbenzenesulfonate | [4-[(E)-[[2-(4-chlorophenoxy)acetyl]hydrazinylidene]methyl]-2-methoxyphenyl] 4-methylbenzenesulfonate | cid_6872703
Type:
Small organic molecule
Emp. Form.:
C23H21ClN2O6S
Mol. Mass.:
488.941
SMILES:
COc1cc(\C=N\NC(=O)COc2ccc(Cl)cc2)ccc1OS(=O)(=O)c1ccc(C)cc1
Structure:
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