Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96599
Substrate
n/a
EC50
>29904±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96599
Synonyms:
1-(benzenesulfonyl)-3-(4-chlorophenyl)-5-(methylthio)-1,2,4-triazole | 1-(benzenesulfonyl)-3-(4-chlorophenyl)-5-methylsulfanyl-1,2,4-triazole | 1-besyl-3-(4-chlorophenyl)-5-(methylthio)-1,2,4-triazole | 3-(4-chlorophenyl)-1-(phenylsulfonyl)-1H-1,2,4-triazol-5-ylmethylsulfide | 3-(4-chlorophenyl)-5-methylsulfanyl-1-(phenylsulfonyl)-1,2,4-triazole | MLS000548841 | SMR000113286 | cid_1051125
Type:
Small organic molecule
Emp. Form.:
C15H12ClN3O2S2
Mol. Mass.:
365.858
SMILES:
CSc1nc(nn1S(=O)(=O)c1ccccc1)-c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: