Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96919
Substrate
n/a
EC50
>29910±n/a nM
Citation
 PubChem, PC Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify TAAR1 Agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96919
Synonyms:
(2S)-2-[[5-[(2-benzoxy-2-keto-ethyl)carbamoyl]-1H-imidazole-4-carbonyl]amino]-4-methyl-valeric acid benzyl ester | (2S)-4-methyl-2-[[oxo-[5-[oxo-[(2-oxo-2-phenylmethoxyethyl)amino]methyl]-1H-imidazol-4-yl]methyl]amino]pentanoic acid (phenylmethyl) ester | (phenylmethyl) (2S)-4-methyl-2-[[5-[(2-oxidanylidene-2-phenylmethoxy-ethyl)carbamoyl]-1H-imidazol-4-yl]carbonylamino]pentanoate | ILP-III-40 | MLS000849543 | SMR000642025 | benzyl (2S)-4-methyl-2-[[5-[(2-oxo-2-phenylmethoxyethyl)carbamoyl]-1H-imidazole-4-carbonyl]amino]pentanoate | cid_24789280
Type:
Small organic molecule
Emp. Form.:
C27H30N4O6
Mol. Mass.:
506.5503
SMILES:
CC(C)C[C@H](NC(=O)c1[nH]cnc1C(=O)NCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1
Structure:
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