Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97194
Substrate
n/a
IC50
>368.85±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97194
Synonyms:
2-[4-[(2,3-dichlorophenyl)methyl]-1-piperazinyl]-5-(phenylmethyl)pyrimidine | 2-[4-[[2,3-bis(chloranyl)phenyl]methyl]piperazin-1-yl]-5-(phenylmethyl)pyrimidine | 5-benzyl-2-[4-(2,3-dichlorobenzyl)piperazino]pyrimidine | 5-benzyl-2-[4-[(2,3-dichlorophenyl)methyl]piperazin-1-yl]pyrimidine | MLS003872358 | SMR002529409 | cid_53385437
Type:
Small organic molecule
Emp. Form.:
C22H22Cl2N4
Mol. Mass.:
413.343
SMILES:
Clc1cccc(CN2CCN(CC2)c2ncc(Cc3ccccc3)cn2)c1Cl
Structure:
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