Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM97356
Substrate
n/a
IC50
>67513±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay PubChem Bioassay (2013)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM97356
Synonyms:
Cyclobendazole | MLS003170852 | N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester | N-[6-[cyclopropyl(oxo)methyl]-1H-benzimidazol-2-yl]carbamic acid methyl ester | SMR001874769 | cid_35803 | methyl N-(6-cyclopropylcarbonyl-1H-benzimidazol-2-yl)carbamate | methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
Type:
Small organic molecule
Emp. Form.:
C13H13N3O3
Mol. Mass.:
259.2606
SMILES:
COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)C1CC1
Structure:
Search PDB for entries with ligand similarity: