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Target
Kallikrein-7
Ligand
BDBM100004
Substrate
n/a
EC50
66092±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100004
Synonyms:
3-(4-bromophenyl)-7-hydroxy-8-(4-morpholinylmethyl)-1-benzopyran-4-one | 3-(4-bromophenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)chromen-4-one | 3-(4-bromophenyl)-7-hydroxy-8-(morpholinomethyl)chromone | 3-(4-bromophenyl)-8-(morpholin-4-ylmethyl)-7-oxidanyl-chromen-4-one | MLS000083050 | SMR000045235 | cid_5389824
Type:
Small organic molecule
Emp. Form.:
C20H18BrNO4
Mol. Mass.:
416.265
SMILES:
Oc1ccc2c(occ(-c3ccc(Br)cc3)c2=O)c1CN1CCOCC1
Structure:
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