Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM128229
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128229
Synonyms:
MLS000772677 | N-(2-methylpropyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanyl)acetamide | N-(2-methylpropyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanyl)ethanamide | N-(2-methylpropyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)acetamide | N-isobutyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)acetamide | SMR000344677 | cid_4882475
Type:
Small organic molecule
Emp. Form.:
C12H16N4OS
Mol. Mass.:
264.347
SMILES:
CC(C)CNC(=O)CSc1nnc2ccccn12
Structure:
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