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TargetRNA polymerase sigma factor SigB (σB)
LigandBDBM226117
Substrate/Competitorn/a
Meas. Tech.Biolayer Interferometry (BLI) Assay
Kd 115±1.4 nM
Citation Vishwanath, SBanerjee, SJamithireddy, AKSrinivasan, NGopal, BChatterjee, J Design, Synthesis, and Experimental Validation of Peptide Ligands Targeting Mycobacterium tuberculosis s Factors. Biochemistry56:2209-2218 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
RNA polymerase sigma factor SigB (σB)
Name:RNA polymerase sigma factor SigB (ϿB)
Synonyms:n/a
Type:Protein
Mol. Mass.:36343.42
Organism:Mycobacterium tuberculosis
Description:P9WGI5
Residue:323
Sequence:
MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEH
LLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGN
LGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKRE
MHQHLGREATDEELAAESGIPIDKINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAM
SAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQ
IERDVMSKLRHGERADRLRSYAS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM226117
NameBDBM226117
Synonyms:ELTPEERLLRAIFGEK | MT2
TypeSmall organic molecule
Emp. Form.C85H141N23O26
Mol. Mass.1901.1675
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(O)=O |r|
Structure
n/a