Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM463872
Substrate
n/a
Meas. Tech.
Radioligand Displacement Assay
Ki
2.70±n/a nM
Citation
 Kunos, G; Iyer, M; Cinar, R; Rice, KC Cannabinoid receptor mediating iminopyrazole compounds US Patent  US10787419 Publication Date 9/29/2020 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1
Type:
Enzyme
Mol. Mass.:
52842.52
Organism:
Mus musculus (Mouse)
Description:
P47746
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM463872
Synonyms:
US10787419, Serial # 72
Type:
Small organic molecule
Emp. Form.:
C26H21ClF3N5O3S
Mol. Mass.:
575.99
SMILES:
CC(=O)NC(=N)C(=N/S(=O)(=O)c1ccc(cc1)C(F)(F)F)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1 |c:25|
Structure:
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