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Target
ADP-ribosylation factor 6
Ligand
BDBM475077
Substrate
n/a
Meas. Tech.
Biochemical Assay1
IC50
8.00±n/a nM
Citation
 Ostanin, K; Shenderovich, M; Bajji, A; Cioffi, CL; Moss, N; Vankayalapati, H; Li, D Arf6 inhibitors and methods of synthesis and use thereof US Patent  US10849901 Publication Date 12/1/2020 
Target
Name:
ADP-ribosylation factor 6
Synonyms:
ARF6 | ARF6_HUMAN
Type:
Protein
Mol. Mass.:
20087.47
Organism:
Human
Description:
P62330
Residue:
175
Sequence:
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
  
Inhibitor
Name:
BDBM475077
Synonyms:
US10849901, Compound 127
Type:
Small organic molecule
Emp. Form.:
C19H16BrNO2
Mol. Mass.:
370.24
SMILES:
OC(=O)c1ccc(cc1)C1Nc2c(Br)cccc2C2C=CCC12 |c:21|
Structure:
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