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Compile Data Set for Download or QSAR
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Found
61
of affinity data for UniProtKB/TrEMBL:
G3GWB4
Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
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Affinity Data
Ki: 0.0300nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 0.0400nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81806
(2-(4,5-dihydro-1h-imidazol-2-yl)-2,3-dihydro-1-(2-...)
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Ki: 0.0500nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81804
(4-chloro-2-(2-imidazolin-2-ylamino)isoindoline | B...)
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Affinity Data
Ki: 0.0800nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 0.120nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81815
(CAS_196343 | L-654,284 | NSC_196343)
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Ki: 0.140nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 0.180nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 0.190nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81803
(CAS_125992 | NSC_125992 | RX 811033)
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Ki: 0.240nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50020192
(8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...)
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Ki: 0.260nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81444
(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)
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Affinity Data
Ki: 0.270nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM30993
(Ajmalicine | MLS000111555 | Raubasine | SMR0001074...)
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Ki: 0.300nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81773
(BAM 1303 | BAM-1303 | CAS_115219-10-8)
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Affinity Data
Ki: 0.380nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81773
(BAM 1303 | BAM-1303 | CAS_115219-10-8)
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Affinity Data
Ki: 0.380nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81816
(AC1L33GU | AR-1K2981 | CAS_82059-49-2 | N-[(2S,11b...)
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Affinity Data
Ki: 0.460nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81807
(ATIPAMEZOLE | CAS_104054-27-5 | NSC_71310)
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Ki: 0.460nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50019855
(2-(4,5-Dihydro-1H-imidazol-2-yl)-5-fluoro-1-methyl...)
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Ki: 0.480nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81809
(BE-2254 | CAS_34772 | NSC_34772)
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Ki: 0.5nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
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Affinity Data
Ki: 0.560nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81810
(CAS_125697 | NSC_125697 | WY 27127)
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Ki: 0.560nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50020192
(8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...)
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Ki: 0.590nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81444
(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)
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Affinity Data
Ki: 0.75nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81808
(CAS_133816 | NSC_133816 | WY 26392)
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Affinity Data
Ki: 0.860nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM30993
(Ajmalicine | MLS000111555 | Raubasine | SMR0001074...)
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Ki: 1.10nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50017720
(1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperi...)
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Ki: 1.30nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM30993
(Ajmalicine | MLS000111555 | Raubasine | SMR0001074...)
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Ki: 1.71nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM66983
(6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazep...)
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Ki: 2.70nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 4.20nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM35256
((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)
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Ki: 5.10nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
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Ki: 9.70nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50030622
((7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13...)
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Ki: 12nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81772
(ARC-239 | CAS_122211 | NSC_122211)
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Ki: 13nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81772
(ARC-239 | CAS_122211 | NSC_122211)
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Ki: 13nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81805
(AZAPETINE | CAS_130-83-6 | NSC_8966)
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Ki: 14nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81813
(CAS_133305 | MPV 295 | NSC_133305)
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Ki: 14nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
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Ki: 15nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
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Ki: 15nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81806
(2-(4,5-dihydro-1h-imidazol-2-yl)-2,3-dihydro-1-(2-...)
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Ki: 18nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50027024
(1-(3-Fluoro-pyridin-2-yl)-piperazine | CHEMBL48833...)
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Ki: 20nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50030622
((7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13...)
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Ki: 20nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM60917
(9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...)
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Ki: 22nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Ki: 28nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
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Ki: 29nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Ki: 31nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Affinity Data
Ki: 31nM
More data for this Ligand-Target Pair
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
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Ki: 37nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
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Ki: 42nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50030623
(6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4...)
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Ki: 43nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM81814
(5H-THIAZOLO[3,2A]PYRIMIDIN-5-ONE, 6-[2-[4-(4-FLUOR...)
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Ki: 51nM
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Target
Alpha-2C adrenergic receptor
(OK)
University of Nebraska
Curated by
PDSP K
i
Database
Ligand
BDBM50240671
((5-Chloro-benzo[1,2,5]thiadiazol-4-yl)-(4,5-dihydr...)
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Ki: 75nM
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