Compile Data Set for Download or QSAR
Report error Found 83 of affinity data for UniProtKB/TrEMBL: O00142
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314845BDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  12nMAssay Description:Competitive inhibition of human recombinant mitochondrial thymidine kinase 2 using ATP as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314845BDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314840BDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314839BDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314848BDBM50314848(3'-hexanoylamino-3'-deoxythymidine | CHEMBL1089836)
Affinity DataKi:  150nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314850BDBM50314850(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-((2S,3S,5...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314838BDBM50314838(3'-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3'-deo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314835BDBM50314835(3'-(4-Butyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-th...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314844BDBM50314844(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200995BDBM50200995(1-[6-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]hexyl]th...)
Affinity DataKi:  290nMAssay Description:Inhibition of TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314837BDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314836BDBM50314836(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201000BDBM50201000(4-[1,1-(diphenyl)-1-[(6-thymin-1-yl)hexyloxy]methy...)
Affinity DataIC50: 390nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314849BDBM50314849(N-methyl-4-((8-(5-methyl-2,4-dioxo-3,4-dihydropyri...)
Affinity DataIC50: 400nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314845BDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  410nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200995BDBM50200995(1-[6-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]hexyl]th...)
Affinity DataIC50: 470nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200990BDBM50200990(1-[6-(triphenylmethoxy)hexyl]thymine | CHEMBL21699...)
Affinity DataIC50: 500nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118490BDBM50118490(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Affinity DataKi:  500nMAssay Description:Inhibition of TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314842BDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314841BDBM50314841(3'-Deoxy-3'-(4-pyridin-2-yl-1,2,3-triazol-1-yl)-be...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118490BDBM50118490(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118490BDBM50118490(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200999BDBM50200999(1-[(Z)-4-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]-2-b...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200992BDBM50200992(4-[1,1-(diphenyl)-1-(Z)-[4-(thymin-1-yl)but-2-enox...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201004BDBM50201004(1-[6-[1-(4-chlorophenyl)-1,1-(diphenyl)methoxy]hex...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200998BDBM50200998(1-[(Z)-4-[1-(4-chlorophenyl)-1,1-(diphenyl)methoxy...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201001BDBM50201001(1-[5-(triphenylmethoxy)pentyl]thymine | CHEMBL2169...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206507BDBM50206507(1-[2'-O-(N-Boc-12-aminododecanoyl)-beta-D-arabinof...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314843BDBM50314843(3'-(5-(4-Chlorophenyl)-1,2,3-triazol-1-yl)-3'-deox...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314847BDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200997BDBM50200997(1-[7-(triphenylmethoxy)heptyl]thymine | CHEMBL2193...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200996BDBM50200996(1-[2-[2-[1-(4-chlorophenyl)-1,1-(diphenyl)methoxy]...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206488BDBM50206488((2R,3S,4R,5R)-2-(5-(2-bromovinyl)-2,4-dioxo-3,4-di...)
Affinity DataIC50: 6.30E+3nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100407BDBM50100407(Octanoic acid 2-[5-((E)-2-bromo-vinyl)-2,4-dioxo-3...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206488BDBM50206488((2R,3S,4R,5R)-2-(5-(2-bromovinyl)-2,4-dioxo-3,4-di...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206496BDBM50206496(1-[2'-O-(N-boc-8-aminooctanoyl)-beta-D-arabinofura...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206484BDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100411BDBM50100411(Decanoic acid 2-[5-((E)-2-bromo-vinyl)-2,4-dioxo-3...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200994BDBM50200994(1-[2-(2-triphenylmethoxyethoxy)ethyl]thymine | CHE...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206491BDBM50206491(CHEMBL70046 | 1-beta-D-arabinofuranosyl-5-(2-bromo...)
Affinity DataKi:  1.04E+4nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375778BDBM50375778(CHEMBL221982)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human mitochondrial thymidine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201005BDBM50201005(N-methyl-4-[1,1-(diphenyl)-1-[6-(thymin-1-yl)hexyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200991BDBM50200991(1-[2-[2-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]ethox...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of [3H]methyl dThd phosphorylation by TK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100412BDBM50100412(CHEMBL392957 | BDBM50206505 | Dodecanoic acid 4-hy...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100412BDBM50100412(CHEMBL392957 | BDBM50206505 | Dodecanoic acid 4-hy...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100409BDBM50100409(CHEMBL400410 | Decanoic acid 4-hydroxy-5-hydroxyme...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100409BDBM50100409(CHEMBL400410 | Decanoic acid 4-hydroxy-5-hydroxyme...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206484BDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dThd substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206491BDBM50206491(CHEMBL70046 | 1-beta-D-arabinofuranosyl-5-(2-bromo...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366680BDBM50366680(CHEMBL605255)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
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