Compile Data Set for Download or QSAR
Report error Found 8381 of affinity data for UniProtKB/TrEMBL: O42275
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204090(CHEMBL3958859)
Affinity DataKi:  0.000590nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50502681(CHEMBL4439521)
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of electric eel AChE by Ellman's colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50560609(CHEMBL4749763)
Affinity DataKi:  0.0417nMAssay Description:Mixed type inhibition of electric eel AChE assessed as inhibition constant using varying levels of acetylthiocholine as substrate by reciprocal Linew...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204086(CHEMBL238756 | Avarol-3''-Thiosalicylate)
Affinity DataKi:  0.0585nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellman ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50557533(CHEMBL4757683)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 0.0800nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellman ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataKi:  0.0820nMAssay Description:Competitive inhibition of Electrophorus electricus AChE using varying levels of acetylthiocholine iodide as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataIC50: 0.0920nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50402577(CHEMBL2206129)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50402583(CHEMBL2206123)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204087(CHEMBL3920392)
Affinity DataKi:  0.221nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50595061(CHEMBL5209357)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435279(CHEMBL2393107)
Affinity DataIC50: 0.299nMAssay Description:Inhibition of electric eel AChE preincubated for 30 mins prior to horseradish peroxidase, H2O2 and DETAPAC addition measured for 20 mins under ROS co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50443517(CHEMBL3087899)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50502695(CHEMBL4535500)
Affinity DataIC50: 0.306nMAssay Description:Inhibition of electric eel AChE by Ellman's colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50557531(CHEMBL4778167)
Affinity DataIC50: 0.307nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50293451(1-Methyl-1-[2-(7-oxo-7H-1-aza-benzo[de]anthracen-9...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of electric eel AChE by LB plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50291665(CHEMBL4165327)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50557530(CHEMBL4761887)
Affinity DataIC50: 0.383nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50422394(CHEMBL3558149)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 6 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50114361(CHEMBL3604192)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of electric eel AChE using ATC iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50292394(4alpha-(hydroxymethyl)-4alpha-demethylterritrem B ...)
Affinity DataIC50: 0.423nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50052204(CHEMBL3318392)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50111776(CHEMBL3605361)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50402576(CHEMBL2206130)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50402587(CHEMBL2206119)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50225209(N,N,N-triethyl-2-(4-(((6-(2-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 0.467nMAssay Description:Inhibition of Electrophorus electricus AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50402590(CHEMBL2205576)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50293451(1-Methyl-1-[2-(7-oxo-7H-1-aza-benzo[de]anthracen-9...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50: 0.492nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435270(CHEMBL2393227)
Affinity DataIC50: 0.495nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 10 mins prior to substrate addition measured every 30 seconds f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50114367(CHEMBL3604198)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of electric eel AChE using ATC iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50114368(CHEMBL3604199)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of electric eel AChE using ATC iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50111774(CHEMBL3605359)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50391537(CHEMBL2147462)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50114365(CHEMBL3604196)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of electric eel AChE using ATC iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50433027(CHEMBL2375941)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435291(CHEMBL2393095)
Affinity DataIC50: 0.604nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 10 mins prior to substrate addition measured every 30 seconds f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50111775(CHEMBL3605360)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435289(CHEMBL2393097)
Affinity DataIC50: 0.648nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 10 mins prior to substrate addition measured every 30 seconds f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435268(CHEMBL2393229)
Affinity DataIC50: 0.776nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 10 mins prior to substrate addition measured every 30 seconds f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50433028(CHEMBL2375940)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435290(CHEMBL2393096)
Affinity DataIC50: 0.932nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 10 mins prior to substrate addition measured every 30 seconds f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against acetylcholinesterase as a prodrug was demonstartedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50292241(CHEMBL4159080)
Affinity DataIC50: 1nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50435278(CHEMBL2393108)
Affinity DataIC50: 1nMAssay Description:Inhibition of electric eel AChE preincubated for 30 mins prior to horseradish peroxidase, H2O2 and DETAPAC addition measured for 20 mins under ROS co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50211239(1-methyl-1-[2-(7-oxo-7H-1-aza-benzo[de]anthracen-9...)
Affinity DataIC50: 1.06nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
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