Compile Data Set for Download or QSAR
Report error Found 1336 of affinity data for UniProtKB/TrEMBL: O75385
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  0.830nMAssay Description:Binding constant for ULK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50643473(CHEMBL5570377)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to 6His/GFP-tagged ULK1 kinase domain (1 to 283 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50612791(CHEMBL5280560)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50637636(CHEMBL5568152)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50637636(CHEMBL5568152)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human ULK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50612793(CHEMBL5266681)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50111572(CHEMBL3605057)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of GST-tagged ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50503137(CHEMBL4516990)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of wild type GST-tagged ULK1 (unknown origin) after 5 mins in presence of gamma-[32]P-ATP by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50503137(CHEMBL4516990)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human ULK1 by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50503137(CHEMBL4516990)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase ULK1(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM379404(6-((4-(cyclopropylamino)-5-(trifluoromethyl)pyrimi...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human ULK1 (1-649) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738005(7-(2-((7-chloro-2-(2-fluoroethyl)- 1,2,3,4-tetrahy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738004(7-(2-((7-cyclopropyl-2-(2- fluoroethyl)-1,2,3,4- t...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738003(4-cyclopropyl-7-(2-((7- cyclopropyl-2- (cyclopropy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738002(4-cyclopropyl-7-(2-((7- cyclopropyl-2-(oxetan-3-yl...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738001(4-cyclopropyl-7-(2-((7- cyclopropyl-2-ethyl-1,2,3,...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738000(7-(2-((6-cyclopropyl-1,2,3,4- tetrahydroisoquinoli...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737999(7-(2-((6-cyclopropyl-1,2,3,4- tetrahydroisoquinoli...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738014(7-(2-((7-chloro-2- (cyclopropylmethyl)-1,2,3,4- te...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738013(7-(2-((7-cyclopropyl-2-ethyl- 1,2,3,4-tetrahydrois...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738012(7-(2-((7-cyclopropyl-2-ethyl- 1,2,3,4-tetrahydrois...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738011(7-(2-((7-chloro-2-(2-fluoroethyl)- 1,2,3,4-tetrahy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738010(4-cyclopropyl-7-(2-((2- (cyclopropylmethyl)-7-ethy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738009(4-cyclopropyl-7-(2-((2- cyclopropyl-4-(1- (cyclopr...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738008(4-cyclopropyl-7-(2-((2- cyclopropyl-4-(piperidin-4...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738007(4-cyclopropyl-7-(2-((2- cyclopropyl-4-(piperazin-1...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737990(7-(2-((2,7-diethyl-1,2,3,4- tetrahydroisoquinolin-...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737989(4-cyclobutyl-7-(2-((6-ethyl-1,2,3,4- tetrahydroiso...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737988(4-cyclopropyl-7-(2-((6-ethyl- 1,2,3,4-tetrahydrois...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737987(7-(2-((7-cyclopropyl-1,2,3,4- tetrahydroisoquinoli...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737986(4-cyclobutyl-7-(2-((7-cyclopropyl- 1,2,3,4-tetrahy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737985(7-(2-((2-chloro-4-(4-(oxetan-3- ylmethyl)piperazin...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737984(4-methyl-7-(2-((7-methyl-2- (oxetan-3-ylmethyl)-1,...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737983(7-(2-((7-cyclopropyl-1,2,3,4- tetrahydroisoquinoli...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737998(7-(2-((6-chloro-1,2,3,4- tetrahydroisoquinolin-7-y...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737997(7-(2-((7-ethyl-1,2,3,4- tetrahydroisoquinolin-6-yl...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737996(4-cyclopropyl-7-(2-((2,7-diethyl- 1,2,3,4-tetrahyd...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737995(7-(2-((7-chloro-2-(2-fluoroethyl)- 1,2,3,4-tetrahy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737994(4-cyclobutyl-7-(2-((7-cyclopropyl- 2-ethyl-1,2,3,4...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737993(4-cyclobutyl-7-(2-((6-cyclopropyl- 1,2,3,4-tetrahy...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737992(4-cyclopropyl-7-(2-((6- cyclopropyl-1,2,3,4- tetra...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737991(7-(2-((2-(cyclopropylmethyl)-7- ethyl-1,2,3,4-tetr...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738038(7-(2-((6-cyclopropyl-1,2,3,4- tetrahydroisoquinoli...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738037(4-cyclopropyl-7-(2-((7-isopropyl-2- (oxetan-3-ylme...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738036(4-cyclopropyl-7-(2-((2- (cyclopropylmethyl)-7-isop...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738035(4-cyclopropyl-7-(2-((2-ethyl-7- isopropyl-1,2,3,4-...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738034(4-cyclopropyl-7-(2-((2-ethyl-4-(4- (oxetan-3-ylmet...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738033(4-cyclopropyl-7-(2-((4-(4- (cyclopropylmethyl)pipe...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738032(4-cyclopropyl-7-(2-((2-ethyl-4- (piperazin-1-yl)ph...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738031(4-cyclopropyl-7-(2-((7-isopropyl- 1,2,3,4-tetrahyd...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

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