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Report error Found 43 of affinity data for UniProtKB/TrEMBL: O75608
LigandPNGBDBM207992(ML349)
Affinity DataKi:  180nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [I75L,S82A](Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  300nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [L176M](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  340nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [Q83P](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [I75L](Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496627(CHEMBL3133032)
Affinity DataKi:  990nMAssay Description:Inhibition of APT1 (unknown origin) by enzyme kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1 [I75L,S82A](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P](Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi:  1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1 [I75L](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  2.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcyl-protein thioesterase 1 [Q83P](Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1 [L176M](Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496629(CHEMBL3133031)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of APT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of APT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496626(CHEMBL1903566)
Affinity DataIC50:  17nMAssay Description:Inhibition of human APT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496628(CHEMBL3133034)
Affinity DataIC50:  27nMAssay Description:Inhibition of APT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496625(CHEMBL3133033)
Affinity DataIC50: <30nMAssay Description:Inhibition of human APT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496630(CHEMBL3133035)
Affinity DataIC50:  148nMAssay Description:Inhibition of APT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92717(Phenylboronic acid, 8)
Affinity DataIC50:  510nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  670nMAssay Description:Inhibition of APT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50282567(3,4-Dichlorophenyl boronic acid | 3,4-dichloro ben...)
Affinity DataIC50:  1.10E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92718(Phenylboronic acid, 10)
Affinity DataIC50:  1.40E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM26139(1-benzothiophen-2-ylboranediol | 1-benzothiophen-2...)
Affinity DataIC50:  2.30E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92719(Phenylboronic acid, 12)
Affinity DataIC50:  2.60E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92720(Phenylboronic acid, 13)
Affinity DataIC50:  2.70E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92722(Phenylboronic acid, 15)
Affinity DataIC50:  3.20E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92721(Phenylboronic acid, 14)
Affinity DataIC50:  3.20E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92723(Phenylboronic acid, 16)
Affinity DataIC50:  3.70E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92724(Phenylboronic acid, 17)
Affinity DataIC50:  3.90E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92725(Phenylboronic acid, 18)
Affinity DataIC50:  4.60E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92726(Phenylboronic acid, 19)
Affinity DataIC50:  6.30E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50211276(CHEMBL1891894)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human APT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92727(Phenylboronic acid, 20)
Affinity DataIC50:  1.02E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM26140(1-benzofuran-2-ylboranediol | 1-benzofuran-2-ylbor...)
Affinity DataIC50:  1.35E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Affinity DataIC50:  1.48E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50:  1.69E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM92728(Phenylboronic acid, 7)
Affinity DataIC50:  3.36E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM26137((2-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50: >5.00E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed