Compile Data Set for Download or QSAR
Report error Found 108 of affinity data for UniProtKB/TrEMBL: P00176
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027783(2-Ethynyl Naphtalene | CHEMBL1743361)
Affinity DataKi:  80nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-ethoxycoumarin O-deethylase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027784(9-Ethynyl Phenanthrene | CHEMBL1908227)
Affinity DataKi:  140nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-pentoxyresorufin O-deethylation activity (PROD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50003140(CHEMBL541325 | Methyl-(1-methyl-hexyl)-prop-2-ynyl...)
Affinity DataKi:  800nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-pentoxyresorufin O-deethylation activity (PROD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataKi:  1.05E+3nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-EFC O-deethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50330386(4-(4'-hydroxy-phenylamino)-4-oxo propanoic acid | ...)
Affinity DataKd:  1.12E+3nMAssay Description:Binding affinity to rat CYP2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataKi:  1.50E+3nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-EFC O-deethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310823(bergamottin | CHEMBL1078442)
Affinity DataKi:  2.40E+3nMAssay Description:Mechanism based inhibition of rat cytochrome P450 2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027787(N-Methylcarbazole | CHEMBL1908211)
Affinity DataKi:  5.20E+3nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50240520(benzyl isothiocyanate | BITC, 17 | Isothiocyanic a...)
Affinity DataKi:  5.80E+3nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-EFC O-deethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM24656(CHEMBL14145 | 4-phenyl-1H-imidazole | 4-Phenylimid...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50017716(CHEMBL282567 | 2-Benzhydryl-pentanoic acid 2-dieth...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404883(CHEMBL169858)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404886(CHEMBL169709)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataKi:  1.10E+4nMAssay Description:Mechanism based inhibition of rat cytochrome P450 2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50418085(CHEMBL1743344)
Affinity DataKi:  1.20E+4nMAssay Description:Mechanism based inhibition of rat cytochrome P450 2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404941(CHEMBL353984)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404855(CHEMBL158007)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404888(CHEMBL169203)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404855(CHEMBL158007)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404893(CHEMBL355666)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404902(CHEMBL355669)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404903(CHEMBL172621)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM39194(MLS000034982 | cid_648179 | (1H-Benzoimidazol-5-yl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404916(CHEMBL171325)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404936(CHEMBL169212)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404925(CHEMBL354972)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50330387(1H-pyrrolidine-1-(4'-hydroxyphenyl)-2,5-dione | CH...)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to rat CYP2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404896(CHEMBL355280)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404930(CHEMBL170998)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404905(CHEMBL170513)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404852(CHEMBL345675)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404944(CHEMBL424396)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404942(CHEMBL353595)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404852(CHEMBL345675)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404934(CHEMBL172156)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404907(CHEMBL172114)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404931(CHEMBL354514)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404938(CHEMBL170771)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404932(CHEMBL169149)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404909(CHEMBL352972)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404891(CHEMBL353945)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50418086(Thioplex | THIOTEPA)
Affinity DataKi:  3.10E+4nMAssay Description:Mechanism based inhibition of rat cytochrome P450 2B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404921(CHEMBL171191)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50240909(2-phenethyl-1H-benzo[d]imidazole | 2-Phenethyl-1H-...)
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404904(CHEMBL170910)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404926(CHEMBL355159)
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404940(CHEMBL169701)
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404854(CHEMBL155867)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404854(CHEMBL155867)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50404853(CHEMBL156313)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
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