Compile Data Set for Download or QSAR
Report error Found 599 of affinity data for UniProtKB/TrEMBL: P03138
TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289776(US10093673, Compound 5.2)
Affinity DataEC50:  0.100nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289769(US10093673, Compound 1.1)
Affinity DataEC50:  0.100nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289772(US10093673, Compound 3.1)
Affinity DataEC50:  0.300nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289774(US10093673, Compound 4.1)
Affinity DataEC50:  0.300nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289779(US10093673, Compound 7.1)
Affinity DataEC50:  0.800nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246818(Cis-11-isobutoxy-10-methoxy-3,3-dimethyl-7-oxo-1,2...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246831(Cis-11-((6-hydroxyhexyl)oxy)-10-methoxy-3,3-dimeth...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246811(cis-10-methoxy-11-(3-methoxypropoxy)-3,3-dimethyl-...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM519994((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  1nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289781(US10093673, Compound 8.1)
Affinity DataEC50:  1nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246819(Cis-11-(cyclopropylmethoxy)-10-methoxy-3,3-dimethy...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246850(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(pyrrolidin-1...)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246832(Cis-11-((6-((tert-butoxycarbonyl)amino)hexyl)oxy)-...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289745(US10093671, Example 14)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289746(US10093671, Example 15)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246829(Cis-10-methoxy-3,3-dimethyl-11-(3-(methylthio)prop...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246835(Cis-10-methoxy-3,3-dimethyl-11-((6-(methylsulfonam...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246817(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(2,2,2-triflu...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540695(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  3nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246812(US10053461, 3 | US10053461, 4 | Cis-11-(benzyloxy)...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246812(US10053461, 3 | US10053461, 4 | Cis-11-(benzyloxy)...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289734(US10093671, Example 3)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289767(US10093671, Example 36)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246823(Cis-11-(3-hydroxy-2,2-dimethylpropoxy)-10-methoxy-...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540719((E)-3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-...)
Affinity DataEC50:  3nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246837(cis-13-chloro-12-(3-methoxypropoxy)-2-oxo-2,5a,6,7...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289756(US10093671, Example 25)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289758(US10093671, Example 27)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM520012(US11142527, Example 44)
Affinity DataEC50:  3.60nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM520067(US11142527, Example 134)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246821(Cis-11-(3-cyanopropoxy)-10-methoxy-3,3-dimethyl-7-...)
Affinity DataIC50: 4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540689(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246820(Cis-10-methoxy-11-(2-methoxyethoxy)-3,3-dimethyl-7...)
Affinity DataIC50: 4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540694(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540693(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289762(US10093671, Example 31)
Affinity DataIC50: 4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM519990(3-((R)-4-(4-((S)-7-(((R)-6-(2-chloro-4-fluoropheny...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540700(US11261190, Example 24)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540732(US11261190, Example 60B)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM519996(1-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289757(US10093671, Example 26)
Affinity DataIC50: 4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540707((R)-methyl 6-(((S)-2-(4-acetylphenyl)-3-oxohexahyd...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM520042((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  4.20nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289743(US10093671, Example 12)
Affinity DataIC50: 5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246816(Cis-10,11-dimethoxy-3,3-dimethyl-7-oxo-1,2,3,3a,7,...)
Affinity DataIC50: 5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540712(3-(3-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289777(US10093673, Compound 6.1 | US10093673, Compound 6....)
Affinity DataEC50:  5nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289750(US10093671, Example 19)
Affinity DataIC50: 5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246822(Cis-11-(3-hydroxypropoxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50: 5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM540691(2-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

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