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Report error Found 353 of affinity data for UniProtKB/TrEMBL: P17516
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427622BDBM50427622(CHEMBL2323508 | US9346803, Table 2, Compound 10: 3...)
Affinity DataIC50: 1.95nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427624BDBM50427624(CHEMBL2323522 | US9346803, Table 2, Compound 11: 9...)
Affinity DataIC50: 3.15nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427620BDBM50427620(CHEMBL2323507 | US9346803, 2)
Affinity DataIC50: 3.51nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427619BDBM50427619(CHEMBL2323511 | US9346803, 3)
Affinity DataIC50: 12.6nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50293598BDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50: 48.7nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427628BDBM50427628(CHEMBL2323472 | US9346803, Table 2, Compound 8: 2-...)
Affinity DataIC50: 49.8nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665020BDBM50665020(CHEMBL6171622)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427626BDBM50427626(CHEMBL2323481 | US9346803, Table 2, Compound 5: 2-...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427625BDBM50427625(CHEMBL178687 | US9346803, Table 2, Compound 6: 3-[...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427621BDBM50427621(CHEMBL2323490 | US9346803, 1)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427627BDBM50427627(CHEMBL2323474 | US9346803, Table 2, Compound 9: 2-...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427629BDBM50427629(CHEMBL179587 | US9346803, Table 2, Compound 7: 2-[...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665008BDBM50665008(CHEMBL6175015)
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665004BDBM50665004(CHEMBL6150439)
Affinity DataIC50: 240nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50664999BDBM50664999(CHEMBL6165313)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665015BDBM50665015(CHEMBL6165285)
Affinity DataIC50: 310nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660824BDBM50660824(CHEMBL6144459)
Affinity DataIC50: 320nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665016BDBM50665016(CHEMBL6176177)
Affinity DataIC50: 330nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241828BDBM50241828(CHEMBL4089817)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human AKR1C4 using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50595596BDBM50595596(CHEMBL5203670)
Affinity DataIC50: 360nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50595596BDBM50595596(CHEMBL5203670)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665002BDBM50665002(CHEMBL6151784)
Affinity DataIC50: 370nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665001BDBM50665001(CHEMBL6152267)
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660825BDBM50660825(CHEMBL6164956)
Affinity DataIC50: 430nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665000BDBM50665000(CHEMBL6176901)
Affinity DataIC50: 450nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665019BDBM50665019(CHEMBL6175880)
Affinity DataIC50: 480nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665007BDBM50665007(CHEMBL6175545)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665021BDBM50665021(CHEMBL6162926)
Affinity DataIC50: 510nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665003BDBM50665003(CHEMBL6169938)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665013BDBM50665013(CHEMBL6169281)
Affinity DataIC50: 630nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660805BDBM50660805(CHEMBL6162896)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50595592BDBM50595592(CHEMBL5179823)
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665014BDBM50665014(CHEMBL6170977)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50241817BDBM50241817(CHEMBL4081954)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human AKR1C4 using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660808BDBM50660808(CHEMBL6133488)
Affinity DataIC50: 830nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665012BDBM50665012(CHEMBL6171081)
Affinity DataIC50: 1.09E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665005BDBM50665005(CHEMBL6160647)
Affinity DataIC50: 1.13E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665010BDBM50665010(CHEMBL6159600)
Affinity DataIC50: 1.17E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50623997BDBM50623997(CHEMBL5412756)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50623994BDBM50623994(CHEMBL5436517)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660826BDBM50660826(CHEMBL6166683)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50595592BDBM50595592(CHEMBL5179823)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665018BDBM50665018(CHEMBL6168606)
Affinity DataIC50: 1.46E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665006BDBM50665006(CHEMBL6169489)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50623966BDBM50623966(CHEMBL5398973)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50665017BDBM50665017(CHEMBL6175007)
Affinity DataIC50: 1.65E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660810BDBM50660810(CHEMBL6134466)
Affinity DataIC50: 1.78E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50427622BDBM50427622(CHEMBL2323508 | US9346803, Table 2, Compound 10: 3...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human recombinant AKR1C4-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50660809BDBM50660809(CHEMBL6148869)
Affinity DataIC50: 2.21E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50029207BDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant GST-tagged AKR1C4 expressed in Escherichia coli using S-tetralol as substrate by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
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