Compile Data Set for Download or QSAR
Report error Found 255 of affinity data for UniProtKB/TrEMBL: P19174
LigandChemical structure of BindingDB Monomer ID 50037076BDBM50037076(CHEMBL3355737)
Affinity DataIC50: 180nMAssay Description:Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50037063BDBM50037063(CHEMBL3355726)
Affinity DataIC50: 540nMAssay Description:Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 98786BDBM98786(US9695200, 32)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99786BDBM99786(US9695200, 49)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108039BDBM108039(US9695200, 80)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99737BDBM99737(US9695200, 46)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 87738BDBM87738(US9695200, 11)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 100784BDBM100784(US9695200, 62)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88535BDBM88535(US9695200, 20)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 100881BDBM100881(US9695200, 67)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99790BDBM99790(US9695200, 50)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 81141BDBM81141(US9695200, 6)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88562BDBM88562(US9695200, 24)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 98821BDBM98821(US9695200, 41)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108388BDBM108388(US9695200, 89)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99847BDBM99847(US9695200, 57)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 103397BDBM103397(US9695200, 72)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88551BDBM88551(US9695200, 22)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 98760BDBM98760(US9695200, 28)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 100765BDBM100765(US9695200, 61)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 107952BDBM107952(US9695200, 76)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88670BDBM88670(US9695200, 26)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108763BDBM108763(US9695200, 91)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99857BDBM99857(US9695200, 59)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88653BDBM88653(US9695200, 25)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 107352BDBM107352(US9695200, 74)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 84007BDBM84007(SMR001307271 | Cefiximum [Latin] | cid_5362065 | M...)
Affinity DataIC50: 1.21E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 34905BDBM34905(1,6-dimethyl-3-propyl-pyrimido[5,4-e][1,2,4]triazi...)
Affinity DataIC50: 1.51E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 52817BDBM52817(2-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-o...)
Affinity DataIC50: 1.51E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114297BDBM114297(dimethyl 2-[(3R,6S)-1-acetyl-6-[(4-methylphenyl)su...)
Affinity DataIC50: 2.03E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 18136BDBM18136(alpha, beta-methyleneadenosine 5 -diphosphate | ci...)
Affinity DataIC50: 2.20E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 50037060BDBM50037060(CHEMBL3355311)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114292BDBM114292(2-(2-cyano-3-pyridinyl)-2-methylpropanoic acid met...)
Affinity DataIC50: 2.70E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 99779BDBM99779(US9695200, 48)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 87754BDBM87754(US9695200, 12)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108352BDBM108352(US9695200, 84)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108346BDBM108346(US9695200, 83)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99793BDBM99793(US9695200, 51)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88558BDBM88558(US9695200, 23)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108382BDBM108382(US9695200, 88)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99802BDBM99802(US9695200, 56)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 88537BDBM88537(US9695200, 21)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99799BDBM99799(US9695200, 54)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 108810BDBM108810(US9695200, 92)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 99852BDBM99852(US9695200, 58)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 100840BDBM100840(US9695200, 64)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 98779BDBM98779(US9695200, 30)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 98772BDBM98772(US9695200, 29)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 98793BDBM98793(US9695200, 33)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 100870BDBM100870(US9695200, 66)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

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