Affinity DataKi: 0.350nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Mixed-type inhibition of AChE in mouse cerebral cortex using acetylthiocholine iodide as substrate by double reciprocal Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.700nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of mouse AChE assessed as inhibition constant using acetylthiocholine iodide as substrate measured every 2 mins by lineweaver-burk plot an...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
Affinity DataKi: 18nM ΔG°: -44.2kJ/molepH: 7.0 T: 25°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -37.7kJ/molepH: 7.0 T: 25°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
Affinity DataKi: 310nM ΔG°: -37.1kJ/molepH: 7.0 T: 25°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
Affinity DataKi: 460nM ΔG°: -36.2kJ/molepH: 7.0 T: 25°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 910nMAssay Description:Competitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 970nMAssay Description:Competitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]methylscopolamine [3H]NMS from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
Affinity DataKi: 2.23E+3nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
Affinity DataKi: 2.26E+3nM IC50: 1.67E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 2.28E+3nM IC50: 1.39E+3nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 2.54E+3nM IC50: 1.36E+3nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 2.67E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
Affinity DataKi: 3.77E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.77E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.84E+3nMAssay Description:Competitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.99E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nM IC50: 490nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 5.06E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.45E+3nM IC50: 4.36E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 5.67E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.68E+3nMAssay Description:Competitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.60E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.36E+3nMAssay Description:Uncompetitive inhibition of albino mouse brain AChE using acetylthiocholine iodide as substrate measured up to 2 mins by Ellmans methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.95E+3nM IC50: 5.11E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 9.04E+3nM IC50: 2.75E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nM ΔG°: -28.7kJ/molepH: 7.0 T: 25°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
Affinity DataKi: 9.90E+3nM IC50: 1.03E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 1.58E+4nM IC50: 5.73E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 1.95E+4nM IC50: 1.07E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
Affinity DataKi: 3.48E+4nM IC50: 1.56E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 4.37E+4nM IC50: 1.66E+3nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 4.68E+4nM IC50: 3.02E+4nMpH: 8.0Assay Description:An aliquot of diluted solution at five different concentration (1, 5, 10,15 and 25 µl) levels was mixed with phosphate buffer (pH 8.0, 3.0 ml), 100 µ...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibitory constant against wild type AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibitory constant against wild type AcetylcholinesteraseMore data for this Ligand-Target Pair
