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TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50262988(CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...)
Affinity DataKd:  4.60E+4nMAssay Description:Binding affinity to mouse AChE by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50292570(decidium | CHEMBL538358)
Affinity DataKd:  7.90E+4nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0.000410nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM31904(Propidium Iodide, 2 | CHEMBL345124 | Propidium | p...)
Affinity DataKd:  1.10E+3nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  18nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50443027(CHEMBL3087794)
Affinity DataKd:  4.44E+4nMAssay Description:Binding affinity to mouse AChE by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50443028(CHEMBL3087815)
Affinity DataKd:  1.48E+4nMAssay Description:Binding affinity to mouse AChE by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50443029(CHEMBL3087809)
Affinity DataKd:  9.20E+3nMAssay Description:Binding affinity to mouse AChE by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50443030(CHEMBL3087808)
Affinity DataKd:  1.11E+4nMAssay Description:Binding affinity to mouse AChE by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50262988(CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...)
Affinity DataKd:  5.40E+4nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50292570(decidium | CHEMBL538358)
Affinity DataKd:  1.60E+5nMAssay Description:Binding affinity to mouse AChE by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50044549(CHEMBL3314093)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462576(CHEMBL4249808)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462577(CHEMBL4243833)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462581(CHEMBL4246013)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462578(CHEMBL4239697)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462580(CHEMBL4239268)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50044548(CHEMBL3314092)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50546263(CHEMBL4749021)
Affinity DataKd:  10nMAssay Description:Binding affinity to mouse ACHE by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50546264(CHEMBL4747937)
Affinity DataKd:  1.00E+7nMAssay Description:Binding affinity to mouse ACHE by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9410(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-ethyl-4-(phe...)
Affinity DataIC50: 0.300nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9410(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-ethyl-4-(phe...)
Affinity DataIC50: 0.301nMAssay Description:Inhibition against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9409(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-methyl-4-(ph...)
Affinity DataIC50: 0.560nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9409(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-methyl-4-(ph...)
Affinity DataIC50: 0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9411(CHEMBL54058 | N-[2-(1-benzylpiperidin-4-yl)ethyl]-...)
Affinity DataIC50: 0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9409(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-methyl-4-(ph...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9409(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-methyl-4-(ph...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM9411(CHEMBL54058 | N-[2-(1-benzylpiperidin-4-yl)ethyl]-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of recombinant mouse AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 0.680nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50004016(CHEMBL544159 | CHEMBL138107 | N-(2-(2-(1-benzylpip...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50004016(CHEMBL544159 | CHEMBL138107 | N-(2-(2-(1-benzylpip...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50029933(2-[3-(1-Benzyl-piperidin-4-yl)-propyl]-5,6-dimetho...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585450(CHEMBL5076277)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of AChE in Swiss Webster mouse cerebral homogenate using acetylthiocholine iodide as substrate preincubated for 10 mins followed substrate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585493(CHEMBL5086036)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50029944(CHEMBL544860 | CHEMBL170946 | 5,6-Dimethoxy-2-[1-(...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50004007(CHEMBL140228 | 2-[2-(1-Benzyl-piperidin-4-yl)-ethy...)
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50467895(CHEMBL4280262)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of AChE in Swiss Webster mouse cerebral homogenate using acetylthiocholine iodide as substrate preincubated for 10 mins followed substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585484(CHEMBL5082836)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50608266(CHEMBL5288285)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585443(CHEMBL5082250)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585455(CHEMBL5088060)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50004001(CHEMBL140999 | 5-Benzoyl-2-[2-(1-benzyl-piperidin-...)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585451(CHEMBL5087922)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585454(CHEMBL5082360)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50585491(CHEMBL5086121)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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