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TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209350BDBM209350(US9266883, 149)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 249396BDBM249396(US9434697, 108 | US9730931, Compound 108 | US10537...)
Affinity DataIC50: 0.100nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen ) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209374BDBM209374(US9266883, 240)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209388BDBM209388(US9266883, 263)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 249396BDBM249396(US9434697, 108 | US9730931, Compound 108 | US10537...)
Affinity DataIC50: 0.200nMAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50559106BDBM50559106(CHEMBL4786195)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 249396BDBM249396(US9434697, 108 | US9730931, Compound 108 | US10537...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209340BDBM209340(US9266883, 115)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209258BDBM209258(US9266883, 16)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50604182BDBM50604182(CHEMBL5194425)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of FGFR4 V550L mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209349BDBM209349(US9266883, 148)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 209349BDBM209349(US9266883, 148)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209345BDBM209345(US9266883, 141)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209277BDBM209277(US9266883, 35)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209342BDBM209342(US9266883, 120)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 681762BDBM681762(US20240199625, Compound 5)
Affinity DataIC50: 0.300nMAssay Description:Compound preparation: Add 45 μL of DMSO to 5 μL of stock solution at a concentration of 10 mM to prepare the solution LY2874455 at 1000 M; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634938BDBM50634938(CHEMBL5523644)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209334BDBM209334(US9266883, 98)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 604879BDBM604879(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50: 0.400nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634964BDBM50634964(CHEMBL5557389)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50554188BDBM50554188(CHEMBL4744686)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal 6x-His tagged FGFR4 catalytic domain (445-753 residues) (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209348BDBM209348(US9266883, 145)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 209334BDBM209334(US9266883, 98)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209354BDBM209354(US9266883, 188)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50559126BDBM50559126(CHEMBL4796410)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 523849BDBM523849(US11136320, Compound 8)
Affinity DataIC50: 0.420nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634942BDBM50634942(CHEMBL5505760)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50593531BDBM50593531(Asp 5878 | Asp-5878 | Asp5878 | ASP-5878 | ASP5878)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) by mobility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 161392BDBM161392(US9108973, 5 | US10124003, Ex. Compound 5 | US1089...)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50644193BDBM50644193(CHEMBL5571683)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal GST tagged cytoplasmic domain human FGFR4 (460 to 802 residues) expressed in Escherichia coli BL21 (DE3) using CSox as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50644192BDBM50644192(CHEMBL5570033)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal GST tagged cytoplasmic domain human FGFR4 (460 to 802 residues) expressed in Escherichia coli BL21 (DE3) using CSox as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50604182BDBM50604182(CHEMBL5194425)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using poly(Glu, Tyr) 4:1 peptide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 161392BDBM161392(US9108973, 5 | US10124003, Ex. Compound 5 | US1089...)
Affinity DataIC50: 0.5nMAssay Description:Purified recombinant human FGFR4 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50604182BDBM50604182(CHEMBL5194425)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type FGFR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50575048BDBM50575048(CHEMBL4866267)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of N-terminal GST fusion tagged human FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634958BDBM50634958(CHEMBL5532250)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209368BDBM209368(US9266883, 228)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 604880BDBM604880(N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-...)
Affinity DataIC50: 0.600nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50559105BDBM50559105(CHEMBL4754106)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209341BDBM209341(US9266883, 118)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209361BDBM209361(US9266883, 205)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634953BDBM50634953(CHEMBL5523440)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634963BDBM50634963(CHEMBL5556836)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 681767BDBM681767(US20240199625, Compound 15)
Affinity DataIC50: 0.630nMAssay Description:Compound preparation: Add 45 μL of DMSO to 5 μL of stock solution at a concentration of 10 mM to prepare the solution LY2874455 at 1000 M; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 681765BDBM681765(US20240199625, Compound 10)
Affinity DataIC50: 0.670nMAssay Description:Compound preparation: Add 45 μL of DMSO to 5 μL of stock solution at a concentration of 10 mM to prepare the solution LY2874455 at 1000 M; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50634940BDBM50634940(CHEMBL5505810)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of FGFR4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209367BDBM209367(US9266883, 227)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 50606159BDBM50606159(CHEMBL5186034)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FGFR4 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4 [388-802](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 209333BDBM209333(US9266883, 95)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Eisai R&D Management

US Patent
LigandChemical structure of BindingDB Monomer ID 209275BDBM209275(US9266883, 33)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
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