Compile Data Set for Download or QSAR
Report error Found 134 of affinity data for UniProtKB/TrEMBL: P22906
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049912(7-(1,1-Dimethyl-propyl)-8-methyl-7H-pyrrolo[3,2-f]...)
Affinity DataKi:  0.00710nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049905(TCMDC-137283 | 7-(1-Ethyl-propyl)-8-methyl-7H-pyrr...)
Affinity DataKi:  0.0300nMAssay Description:Competitive inhibition of Candida albicans DHFR preincubated for 2 mins followed by substrate addition in presence of dihydrofolateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049905(TCMDC-137283 | 7-(1-Ethyl-propyl)-8-methyl-7H-pyrr...)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049911(8-tert-Butyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diam...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049898(TCMDC-137847 | 8-Isopropyl-7H-pyrrolo[3,2-f]quinaz...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049899(TCMDC-137864 | 7-Isopropyl-8-methyl-7H-pyrrolo[3,2...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18043(CHEMBL318721 | 5-(pentan-3-yl)-5,10,12-triazatricy...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049914(7-(3,4,5-Trimethoxy-benzyl)-7H-pyrrolo[3,2-f]quina...)
Affinity DataKi:  0.230nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049902(TCMDC-137851 | 7,8-Diethyl-7H-pyrrolo[3,2-f]quinaz...)
Affinity DataKi:  0.330nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049913(TCMDC-137856 | 7-Ethyl-8-isopropyl-7H-pyrrolo[3,2-...)
Affinity DataKi:  0.330nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049896(8-Butyl-7-tert-butyl-7H-pyrrolo[3,2-f]quinazoline-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049910(7-Ethyl-8-propyl-7H-pyrrolo[3,2-f]quinazoline-1,3-...)
Affinity DataKi:  0.650nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049915(8-Ethyl-7-methyl-7H-pyrrolo[3,2-f]quinazoline-1,3-...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049908(7,8-Dimethyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diam...)
Affinity DataKi:  2nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18043(CHEMBL318721 | 5-(pentan-3-yl)-5,10,12-triazatricy...)
Affinity DataIC50: 4nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18047(5-[(4-tert-butylphenyl)sulfanyl]quinazoline-2,4-di...)
Affinity DataIC50: 8nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298801(Biphenyl antifolate, 2 | CHEMBL575217 | US8853228,...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298811((S)-5-(3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)bu...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298810((R)-5-(3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)bu...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429695(CHEMBL2335421)
Affinity DataIC50: 17nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007898(CHEMBL3234317)
Affinity DataIC50: 18nMAssay Description:Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM26521(6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-y...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298813((S)-6-ethyl-5-(3-(3,4,5-trimethoxyphenyl)but-1-yny...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298812((R)-6-ethyl-5-(3-(3,4,5-trimethoxyphenyl)but-1-yny...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329607(5-(3-(3-methoxybiphenyl-4-yl)but-1-ynyl)-6-methylp...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298805((+/-)-6-ethyl-5-(3-(3,4,5-trimethoxyphenyl)but-1-y...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429700(CHEMBL2335416)
Affinity DataIC50: 21nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298815((S)-5-(3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-y...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298814(5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298800(CHEMBL584391 | Biphenyl antifolate, 3 | US8853228,...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298800(CHEMBL584391 | Biphenyl antifolate, 3 | US8853228,...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18046(CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...)
Affinity DataIC50: 23nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429699(CHEMBL2335417)
Affinity DataIC50: 23nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007902(CHEMBL3234321)
Affinity DataIC50: 23nMAssay Description:Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | TCMDC-1...)
Affinity DataKi:  23nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429693(CHEMBL2335423)
Affinity DataIC50: 23nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049900(7-Methyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine ...)
Affinity DataKi:  25nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298817(5-((3S)-3-(2-methoxy-2'-methylbiphenyl-4-yl)but-1-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298816(5-((3R)-3-(2-methoxy-2'-methylbiphenyl-4-yl)but-1-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25823(5-{3-[3-methoxy-4-(2-methylphenyl)phenyl]but-1-yn-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298809(CHEMBL572485 | Biphenyl antifolate, 25 | (+/-)-5-(...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298819((S)-5-(3-(4',5-dimethoxybiphenyl-3-yl)but-1-ynyl)-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007817(CHEMBL3234115)
Affinity DataIC50: 30nMAssay Description:Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298818((R)-5-(3-(4',5-dimethoxybiphenyl-3-yl)but-1-ynyl)-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25824(5-{3-[4-(2,6-dimethylphenyl)-3-methoxyphenyl]but-1...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298821((S)-5-(3-(2-methoxy-2',6'-dimethylbiphenyl-4-yl)bu...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298820((R)-5-(3-(2-methoxy-2',6'-dimethylbiphenyl-4-yl)bu...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Yeast)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25826(5-[(3R)-3-(3-methoxy-5-phenylphenyl)but-1-yn-1-yl]...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
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