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TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50571007(CHEMBL4439634)
Affinity DataKd:  0.00540nMAssay Description:Inhibition of human recombinant CA6 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503811(CHEMBL4567746)
Affinity DataKd:  0.00540nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503808(CHEMBL4441730)
Affinity DataKd:  0.0670nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503816(CHEMBL4573916)
Affinity DataKd:  0.0730nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503786(CHEMBL4555622)
Affinity DataKd:  0.0920nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503780(CHEMBL4475315)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503805(CHEMBL4474251)
Affinity DataKd:  0.120nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503798(CHEMBL4517728)
Affinity DataKd:  0.140nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503776(CHEMBL4560953)
Affinity DataKd:  0.150nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503795(CHEMBL4463683)
Affinity DataKd:  0.160nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504897(CHEMBL4562296)
Affinity DataKd:  0.170nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503810(CHEMBL4462447)
Affinity DataKd:  0.170nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449837(CHEMBL4176862)
Affinity DataKd:  0.190nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449819(CHEMBL4165570)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504905(CHEMBL4442511)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50025094(4-Nitro-benzenesulfonamide | 4-nitrobenzenesulfona...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449819(CHEMBL4165570)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503800(CHEMBL4558235)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503807(CHEMBL4587295)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449816(CHEMBL4160149)
Affinity DataKd:  0.240nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503781(CHEMBL4464359)
Affinity DataKd:  0.25nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503815(CHEMBL4516072)
Affinity DataKd:  0.260nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503778(CHEMBL4443078)
Affinity DataKd:  0.270nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449816(CHEMBL4160149)
Affinity DataKd:  0.270nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503806(CHEMBL4553790)
Affinity DataKd:  0.270nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504900(CHEMBL4574321)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504952(CHEMBL4466140)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50025093(p-Halide-sulfanilamide derivative, 2 | P-Chloroben...)
Affinity DataKi:  0.300nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449836(CHEMBL4166643)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504927(CHEMBL4444201)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449836(CHEMBL4166643)
Affinity DataKd:  0.330nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503784(CHEMBL4539340)
Affinity DataKd:  0.350nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503775(CHEMBL4439909)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503799(CHEMBL4474833)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503775(CHEMBL4439909)
Affinity DataKd:  0.370nMAssay Description:Inhibition of human recombinant CA6 assessed as intrinsic dissociation constant by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449815(CHEMBL4168966)
Affinity DataKd:  0.380nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503813(CHEMBL4457904)
Affinity DataKd:  0.380nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503793(CHEMBL4461481)
Affinity DataKd:  0.380nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503797(CHEMBL4516858)
Affinity DataKd:  0.380nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503801(CHEMBL4446249)
Affinity DataKd:  0.390nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50449835(CHEMBL4170371)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503809(CHEMBL4567916)
Affinity DataKd:  0.410nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503796(CHEMBL4449149)
Affinity DataKd:  0.430nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504947(CHEMBL4517317)
Affinity DataKd:  0.440nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504913(CHEMBL4436290)
Affinity DataKd:  0.440nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504912(CHEMBL4451500)
Affinity DataKd:  0.450nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50504950(CHEMBL4573963)
Affinity DataKd:  0.530nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503777(CHEMBL4473602)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50503790(CHEMBL4458989)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  0.560nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
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