Compile Data Set for Download or QSAR
Report error Found 379 of affinity data for UniProtKB/TrEMBL: P30536
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274351(2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274351(2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.188nMAssay Description:In vitro binding affinity for PBR (peripheral benzodiazepine receptor) in monkey brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.242nMAssay Description:Displacement of [3H]PK11195 from human PBR receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.242nMAssay Description:Binding affinity to PBR in human mitochondrial tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50622779(CHEMBL5428961)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to TSPO receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50421116(CHEMBL2088374)
Affinity DataKi:  0.280nMAssay Description:Binding affinity to TSPO (unknown origin) relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50409613(CHEMBL5275028)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to mitochondrial TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50060095(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Affinity DataKi:  0.410nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50060095(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Affinity DataKi:  0.410nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM98172(US8492379, 28)
Affinity DataKi:  0.450nMAssay Description:In vitro binding activity of TSPO.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
US Patent

TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM98171(US8492379, 27)
Affinity DataKi:  0.460nMAssay Description:In vitro binding activity of TSPO.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
US Patent

TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataKi:  0.537nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataKi:  0.537nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274561(4-(2-(4-Chlorophenyl)-3-(2-(dipropylamino)-2-oxoet...)
Affinity DataKi:  0.860nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274561(4-(2-(4-Chlorophenyl)-3-(2-(dipropylamino)-2-oxoet...)
Affinity DataKi:  0.860nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50073588(CHEMBL3408974)
Affinity DataKi:  0.870nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274259(N-Butyl-2-(6,8-dichloro-2-(4-methoxyphenyl)imidazo...)
Affinity DataKi:  0.882nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274259(N-Butyl-2-(6,8-dichloro-2-(4-methoxyphenyl)imidazo...)
Affinity DataKi:  0.882nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50185957(N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50185957(N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM98173(US8492379, 29)
Affinity DataKi:  0.970nMAssay Description:In vitro binding activity of TSPO.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
US Patent

TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50390852(CHEMBL2070799)
Affinity DataKi:  0.997nMAssay Description:Binding affinity to human TSPO assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50255877(N-Fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyan...)
Affinity DataKi:  0.997nMAssay Description:Displacement of [3H]PK11195 from human PBR receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50350912(CHEMBL1817978)
Affinity DataKi:  1.19nMAssay Description:Displacement of [3H]PK11195 from TSPO in human HEK293 mitochondrial fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50229593(N-acetyl-N-(2-methoxycarbonylbenzyl)-2-phenoxyanil...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to PBR in human mitochondrial tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM98176(US8492379, 53)
Affinity DataKi:  1.55nMAssay Description:In vitro binding activity of TSPO.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
US Patent

TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50335270(2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  1.57nMAssay Description:Displacement of [11C]PK11195 from high affinity binding site of TSPO in human brain membrane homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50210943(CHEMBL3970955)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50408728(CHEMBL339816)
Affinity DataKi:  1.60nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50408728(CHEMBL339816)
Affinity DataKi:  1.60nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50335270(2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  1.82nMAssay Description:Displacement of [11C]PK11195 from mixed affinity binding site of TSPO in human brain membrane homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50054139((R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic a...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50530439(CHEMBL4456416)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50530439(CHEMBL4456416)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50054139((R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic a...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human TSPO assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50651252(CHEMBL5631700)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to TSPO (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50229594(N-(2-methoxybenzyl)-N-(4-phenoxypyridin-3-yl)aceta...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human mitochondrial TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50363523(CHEMBL1944785)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM98174(US8492379, 30)
Affinity DataKi:  2.40nMAssay Description:In vitro binding activity of TSPO.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
US Patent

TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM279583(US10035780, Compound 7)
Affinity DataKi:  2.5nMAssay Description:For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

Displayed 1 to 50 (of 379 total ) | Next | Last >>
Jump to: