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Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50031895((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  0.120nMAssay Description:Inhibitory activity was measured on rat Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50216164(CHEMBL133338)
Affinity DataIC50: 0.130nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025367(4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]qu...)
Affinity DataIC50: 0.130nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50031877((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  0.170nMAssay Description:Inhibitory activity was measured on rat Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50225985(CHEMBL3349105)
Affinity DataIC50: 0.210nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 0.280nMAssay Description:Inhibitory activity was measured on rat Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025454(1,4,4a,6a-Tetramethyl-2-oxo-hexadecahydro-indeno[5...)
Affinity DataIC50: 0.560nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50031896((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity was measured on rat Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025341(4a,6a-Dimethyl-7-(3-methyl-butyryl)-hexadecahydro-...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215529(CHEMBL39419)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215480(CHEMBL289613)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025450(Sodium; 1,4a,6a-trimethyl-2-oxo-hexadecahydro-inde...)
Affinity DataKi:  1.70nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025450(Sodium; 1,4a,6a-trimethyl-2-oxo-hexadecahydro-inde...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025332(1,4a,6a-Trimethyl-7-(2-methyl-butyryl)-hexadecahyd...)
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50032282(4-(2-{(E)-3-[1-(1-Propyl-butyl)-1H-indol-5-yl]-but...)
Affinity DataIC50: 2.30nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025415(N,N-Diethyl-2-(1,4a,6a-trimethyl-2-oxo-hexadecahyd...)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50057482(ONO-3805 | 4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-etho...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025353(7-(1-Hydroxy-ethyl)-1,4a,6a-trimethyl-hexadecahydr...)
Affinity DataIC50: 2.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215478(CHEMBL289397)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215474(CHEMBL41413)
Affinity DataIC50: 3nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50032297(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025413(4-(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025375(7-Acetyl-1,4a,6a,8-tetramethyl-hexadecahydro-inden...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50405303(CHEMBL2021336)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215475(CHEMBL287716)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50470304(CHEMBL98478)
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025399(Sodium; 4-(1,4a,6a-trimethyl-2-oxo-hexadecahydro-i...)
Affinity DataIC50: 3.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025337(7-(2-Hydroxy-1-methyl-ethyl)-1,4a,6a-trimethyl-hex...)
Affinity DataIC50: 3.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215461(CHEMBL39559)
Affinity DataIC50: 4nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50589275(CHEMBL5190333)
Affinity DataIC50: 4nMAssay Description:Inhibition of rat liver microsomal SRD5A2 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50032281(4-(2-{(E)-3-[1-(1-Propyl-pentyl)-1H-indol-5-yl]-bu...)
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025379(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataIC50: 4.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025330(1',4a',6a'-trimethylspiro[tetrahydrofuran-2,7'-per...)
Affinity DataIC50: 4.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50215530(CHEMBL40847)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50213061(CHEMBL2298601)
Affinity DataKi:  5nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5alpha reductase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50032288(4-{2-[(E)-3-(1-Benzhydryl-1H-indol-5-yl)-but-2-eno...)
Affinity DataIC50: 5.60nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50470291(CHEMBL95410)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50367296(CHEMBL1790284)
Affinity DataKi:  6nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50216167(CHEMBL134224)
Affinity DataIC50: 6.30nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025455(4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]qu...)
Affinity DataIC50: 6.30nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50470283(CHEMBL421752)
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025395((1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-...)
Affinity DataIC50: 6.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 6.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50470301(CHEMBL99824)
Affinity DataIC50: 7.10nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50470289(CHEMBL96030)
Affinity DataIC50: 7.20nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50367296(CHEMBL1790284)
Affinity DataIC50: 7.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025364(2-(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,...)
Affinity DataIC50: 7.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50025359(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataIC50: 7.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50470272(CHEMBL431270)
Affinity DataIC50: 7.80nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase in prostates from male ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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