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Report error Found 2383 for UniProtKB: P32239
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50045797(2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-yl)-2...)
Affinity DataKi: >0.000100nMAssay Description:Tested for inhibition of [3H]pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataEC50:  0.00900nMAssay Description:Ability to stimulate intracellular calcium response was determined using CCK receptor-bearing chinese hamster ovary cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50454480(CHEMBL2093059)
Affinity DataIC50: 0.0540nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50281664(p-Tyr(SO3Na)-gNle-mGly-Trp-(N-Me)Nle-Asp-Phe-NH2 |...)
Affinity DataKi:  0.0600nMAssay Description:Tested for the inhibition of [3H]pCCK-8 binding to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50454481(CHEMBL2110201)
Affinity DataIC50: 0.0740nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50290398(FR-175985 | 1-[1-[2-(3-Aza-bicyclo[3.2.2]non-3-yl)...)
Affinity DataIC50: 0.0870nMAssay Description:Inhibition of [125I]Cholecystokinin-8 binding to Cholecystokinin type B receptor of guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50070467(1-[1-[2-(3-Aza-bicyclo[3.2.2]non-3-yl)-2-oxo-ethyl...)
Affinity DataIC50: 0.0870nMAssay Description:Compound was evaluated for the inhibition of 124 I-CCK-8 binding at Cholecystokinin type B receptor on guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataEC50:  0.0930nMAssay Description:Displacement of [125I]CCK-8 from CCK2 receptor in human FGS7 Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517382(CHEMBL4563364)
Affinity DataIC50: 0.0933nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50059319(1-[(R)-5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-BH CCK-8S from Cholecystokinin type B receptor in guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285009(3-{3-[(3R,5R)-1-(tert-Butylcarbamoyl-methyl)-5-cyc...)
Affinity DataIC50: 0.100nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50059319(1-[(R)-5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285009(3-{3-[(3R,5R)-1-(tert-Butylcarbamoyl-methyl)-5-cyc...)
Affinity DataIC50: 0.100nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50040667(1-[(R)-5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2...)
Affinity DataIC50: 0.100nMAssay Description:Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50004477(N-(1-Carbamoyl-2-phenyl-ethyl)-3-({2-[3-(1H-indol-...)
Affinity DataEC50:  0.100nMAssay Description:Evaluated in vitro for maximal stimulatory activity for amylase release relative to CCK-8 in guinea pig tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50049783(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50411339(CHEMBL227276)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285624((R)-3-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataKd:  0.110nMAssay Description:The equilibrium binding constant to guinea pig cerebral cortex membranes was measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]CCK-8s from human recombinant CCK-B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]CCK-8s from human recombinant CCK2 receptor expressed in CHO cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50046128(2-[2-(2-{2-[2-{2-[3-Carboxy-2-(2-methylamino-3-phe...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]pCCK-8 from cholecystokinin type B receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517332(CHEMBL4522865)
Affinity DataIC50: 0.132nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517359(CHEMBL4534236)
Affinity DataIC50: 0.132nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50449787(PD-134308 | CHEMBL2062154)
Affinity DataIC50: 0.138nMAssay Description:In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50056102(YF-476 | 1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50040674(1-((S)-1-Isobutyl-2-oxo-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataIC50: 0.142nMAssay Description:The compound was tested for binding activity against Cholecystokinin type B receptor from rat pancreatic tissue using [125]BH CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50092393(3-(2-{[2-(2-{2-[2-tert-Butoxycarbonylamino-3-(4-su...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity against cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50016504(Boc-Tyr(SO3Na)-gNle-mGIy-Trp-(N-Me)Nle-Asp-Phe-NH2...)
Affinity DataKi:  0.150nMAssay Description:Tested for the inhibition of [3H]pCCK-8 binding to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517381(CHEMBL4561184)
Affinity DataIC50: 0.151nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517367(CHEMBL4468861)
Affinity DataIC50: 0.158nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517362(CHEMBL4565336)
Affinity DataIC50: 0.166nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50472889(CHEMBL415240)
Affinity DataKi:  0.178nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50016425(3-{2-[2-(2-{2-[2-(tert-Butoxycarbonyl-methyl-amino...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]BH-CCK- binding to cholecystokinin type B receptor from jurkat TcellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50411341(CHEMBL226583)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50049789(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50517384(CHEMBL4443415)
Affinity DataIC50: 0.209nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50472863(CHEMBL333979)
Affinity DataKi:  0.209nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285019(N-tert-Butyl-2-((3R,5R)-5-cyclohexyl-8-methyl-2-ox...)
Affinity DataIC50: 0.220nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21135((3S)-3-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-2-amino-3...)
Affinity DataKi:  0.220nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2008
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50043556(N,N-Diethyl-2-{3-[3-(3-methoxy-phenyl)-ureido]-2-o...)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50472878(CHEMBL331872)
Affinity DataKi:  0.224nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50: 0.229nMAssay Description:Binding affinity against human Cholecystokinin type B receptor by displacement of [125I]CCK-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50016425(3-{2-[2-(2-{2-[2-(tert-Butoxycarbonyl-methyl-amino...)
Affinity DataKi:  0.230nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50043546(1-(3-Methoxy-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrrolidi...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285466(N-Benzoyl-3-[3-(5-cyclohexyl-1-methyl-2-oxo-2,3-di...)
Affinity DataIC50: 0.240nMAssay Description:Binding affinity towards Cholecystokinin type B receptor was measured by displacement of [125I]CCK from guinea pig cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50004490(N-(1-Carbamoyl-2-phenyl-ethyl)-3-(2-{3-(1H-indol-3...)
Affinity DataIC50: 0.240nMAssay Description:Evaluated in vitro for its binding affinity towards cholecystokinin type B receptor of guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002875(CHEMBL388144)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285623((R)-3-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataKd:  0.25nMAssay Description:The equilibrium binding constant to guinea pig cerebral cortex membranes was measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50472863(CHEMBL333979)
Affinity DataKi:  0.251nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50285011(N-tert-Butyl-2-{(3R,5R)-5-cyclohexyl-3-[3-(3-metha...)
Affinity DataIC50: 0.260nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

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