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Report error Found 16 of affinity data for UniProtKB/TrEMBL: P46937
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50626276(CHEMBL5198469)
Affinity DataIC50: 1nMAssay Description:Inhibition of YAP (unknown origin) incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM563559(5-(3-chlorophenoxy)-N-isopropyl-2- naphthamide | U...)
Affinity DataIC50: 100nMAssay Description:Inhibition of YAP in HEK293T cells incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM565701(N-(methylsulfonyl)-5-(4- (trifluoromethyl)phenoxy)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of YAP in HEK293T cells incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM566483(N-(cyanomethyl)-5-(4- (trifluoromethyl)phenoxy)-2-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of YAP in HEK293T cells incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50626274(CHEMBL5429947)
Affinity DataKd:  340nMAssay Description:Binding affinity to N-terminal YAP ( 1 to 291 residues) (unknown origin) expressed in Escherichia coli Rosetta cells assessed as dissociation constan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50626278(CHEMBL5406194)
Affinity DataIC50: 391nMAssay Description:Inhibition of YAP (unknown origin) incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50626277(CHEMBL5398453)
Affinity DataIC50: 454nMAssay Description:Inhibition of YAP (unknown origin) incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50648049(CHEMBL2004687)
Affinity DataKd:  738nMAssay Description:Binding affinity to YAP (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50619177(CHEMBL5423389)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50626274(CHEMBL5429947)
Affinity DataKd:  2.64E+3nMAssay Description:Binding affinity to YAP WW domain (165 to 271 residues) (unknown origin) expressed in Escherichia coli Rosetta cells assessed as dissociation constan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50619182(CHEMBL5421684)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50547126(CHEMBL4763473)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of FAM-labelled GST-tagged full-length YAP (60 to 99 residues)(unknown origin)/N-terminal His-tagged TEAD2(217 to 447 residues) (unknown o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50619186(CHEMBL5437226)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50619187(CHEMBL5431273)
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50619190(CHEMBL5420439)
Affinity DataIC50: 8.67E+4nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50619189(CHEMBL5429883)
Affinity DataIC50: 2.54E+5nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed