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TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347074(US10202390, Example 29)
Affinity DataIC50: 2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347062(US10202390, Example 17)
Affinity DataIC50: 2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347063(US10202390, Example 18)
Affinity DataIC50: 2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347061(3-(4-(isopropylamino)-5-(1-(tetrahydro-2H-pyran-4-...)
Affinity DataIC50: 2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50613996(CHEMBL5281961)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347058(US10202390, Example 13)
Affinity DataIC50: 3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347072(3-(5-(1-(3-hydroxy-3-methylbutyl)-1H-pyrazol-4-yl)...)
Affinity DataIC50: 3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347064(US10202390, Example 19)
Affinity DataIC50: 3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347067(US10202390, Example 22)
Affinity DataIC50: 4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347073(US10202390, Example 28)
Affinity DataIC50: 5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347070(US10202390, Example 25)
Affinity DataIC50: 5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347060(3-(4-(isopropylamino)-5-(4-propyl-1H-1,2,3-triazol...)
Affinity DataIC50: 6nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585716(US11530213, Example 37 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 6nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347056(2-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-N-isopro...)
Affinity DataIC50: 8nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585717(US11530213, Example 38 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 8nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50505262(CHEMBL4559408)
Affinity DataKi:  8.20nMAssay Description:Inhibition GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347059(US10202390, Example 14)
Affinity DataIC50: 9nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347057(US10202390, Example 12)
Affinity DataIC50: 9nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585727(US11530213, Example 48 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 9nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM585727(US11530213, Example 48 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM585715(US11530213, Example 36 | N-(2-((8-chloro-1-(2,6- d...)
Affinity DataIC50: 9nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347068(US10202390, Example 23)
Affinity DataIC50: 9nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347071(US10202390, Example 26)
Affinity DataIC50: 10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585729(US11530213, Example 50 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 11nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50613997(CHEMBL5280047)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347065(US10202390, Example 20)
Affinity DataIC50: 12nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585741(US11530213, Example 62)
Affinity DataIC50: 13nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585719(US11530213, Example 40 | 8-chloro-1-(2,6-chlorophe...)
Affinity DataIC50: 13nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585738(US11530213, Example 59)
Affinity DataIC50: 14nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347066(US10202390, Example 21)
Affinity DataIC50: 14nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347048(US10202390, Example 3)
Affinity DataIC50: 14nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347069(US10202390, Example 24)
Affinity DataIC50: 14nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585721(US11530213, Example 42 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 15nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585718(US11530213, Example 39 | (S)-8-chloro-1-(2,6- dich...)
Affinity DataIC50: 15nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585742(US11530213, Example 63)
Affinity DataIC50: 16nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585737(US11530213, Example 58)
Affinity DataIC50: 17nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347051(US10202390, Example 6)
Affinity DataIC50: 18nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585764(US11530213, Example 85)
Affinity DataIC50: 19nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347055(US10202390, Example 10)
Affinity DataIC50: 20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585760(US11530213, Example 81)
Affinity DataIC50: 23nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585768(US11530213, Example 89)
Affinity DataIC50: 24nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM585709(US11530213, Example 30 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM585709(US11530213, Example 30 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 25nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585694(US11530213, Example 15 | 5-(2,5,8,11,14,17- hexaox...)
Affinity DataIC50: 25nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585722(US11530213, Example 43 | 3,5-dichloro-4-(8-chloro-...)
Affinity DataIC50: 26nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50613999(CHEMBL5289977)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM585732(US11530213, Example 53 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 28nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM585720(US11530213, Example 41 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 28nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347054(US10202390, Example 9)
Affinity DataIC50: 29nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

LigandPNGBDBM585733(US11530213, Example 54 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 29nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

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