Compile Data Set for Download or QSAR
Report error Found 952 of affinity data for UniProtKB/TrEMBL: P51639
LigandChemical structure of BindingDB Monomer ID 50013219BDBM50013219(CHEMBL2375155 | Sodium salt of7-[1-Cyclohexyl-4-(4...)
Affinity DataIC50: 0.106nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20696BDBM20696(sodium (3R,5R)-7-{3-[benzyl(methyl)carbamoyl]-1-(4...)
Affinity DataIC50: 5.90nM EC50:  0.200nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20704BDBM20704(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(3-fluoro...)
Affinity DataIC50: 3.90nM EC50:  0.200nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20708BDBM20708(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(1R...)
Affinity DataIC50: 1.5nM EC50:  0.300nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20713BDBM20713(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(3R)-3-ph...)
Affinity DataIC50: 2nM EC50:  0.300nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20702BDBM20702(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methox...)
Affinity DataIC50: 12nM EC50:  0.300nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50042653BDBM50042653(7-[3-Bromo-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-p...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 18372BDBM18372(CHEMBL1496 | Ros | (3R,5S,6E)-7-[4-(4-fluorophenyl...)
Affinity DataIC50: 3.10nM EC50:  0.300nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20689BDBM20689((3R,5R)-7-[3-(benzylcarbamoyl)-1-(4-fluorophenyl)-...)
Affinity DataIC50: 4.70nM EC50:  0.300nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20712BDBM20712(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-[(3-phenylp...)
Affinity DataIC50: 1.5nM EC50:  0.400nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20690BDBM20690(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methox...)
Affinity DataIC50: 2.80nM EC50:  0.400nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 22158BDBM22158((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methy...)
Affinity DataIC50: 0.5nM EC50:  1.40nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20703BDBM20703(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(2-fluoro...)
Affinity DataIC50: 4.80nM EC50:  0.5nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20705BDBM20705(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-fluoro...)
Affinity DataIC50: 6.60nM EC50:  0.5nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50042654BDBM50042654(7-[3-(3-Bromo-phenyl)-2-(4-fluoro-phenyl)-5-isopro...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20707BDBM20707(sodium (3R,5R)-7-(3-{[(2,3-difluorophenyl)methyl](...)
Affinity DataIC50: 9nM EC50:  0.600nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20700BDBM20700(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(3-...)
Affinity DataIC50: 6.10nM EC50:  0.600nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 18372BDBM18372(CHEMBL1496 | Ros | (3R,5S,6E)-7-[4-(4-fluorophenyl...)
Affinity DataIC50: 3.10nM EC50:  0.600nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20691BDBM20691(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-fluoro...)
Affinity DataIC50: 3.80nM EC50:  0.700nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20693BDBM20693(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-({[3-(metho...)
Affinity DataIC50: 7nM EC50:  0.700nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 18382BDBM18382(disodium 4-[({5-[(3R,5R)-6-carboxylato-3,5-dihydro...)
Affinity DataIC50: 0.850nMpH: 7.2 T: 2°CAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20692BDBM20692(pyrazole-based inhibitor, 35 | sodium (3R,5R)-7-[1...)
Affinity DataIC50: 1.90nM EC50:  0.900nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 22157BDBM22157((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-1...)
Affinity DataIC50: 0.900nM EC50:  1.5nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 22160BDBM22160(sodium 5-({5-[(1E,3S,5R)-6-carboxy-3,5-dihydroxyhe...)
Affinity DataIC50: 0.900nM EC50:  13.7nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50139181BDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of rat liver HMG-CoA reductase pre incubated for 5 mins followed by substrate addition using NADPH as substrate by scintillation counter a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50003240BDBM50003240(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of solubilized, purified rat liver HMG-CoA reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 155389BDBM155389(US9006282, Example 3, Compound 8)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 155390BDBM155390(US9006282, Example 3, Compound 9)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50042607BDBM50042607((E)-(3R,5S)-7-[4,5-Bis-(4-fluoro-phenyl)-2-isoprop...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 18425BDBM18425((3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methylphenyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 155384BDBM155384(US9006282, Example 3, Compound 3)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 155385BDBM155385(US9006282, Example 3, Compound 4)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 155386BDBM155386(US9006282, Example 3, Compound 5)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 22159BDBM22159((3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)...)
Affinity DataIC50: 4.20nM EC50:  1nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50020287BDBM50020287(7-[2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6...)
Affinity DataIC50: 1nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 155374BDBM155374(US9006282, Example 2, Compound 2 | US9102656, Exam...)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50042631BDBM50042631(CHEMBL121727 | (E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50014828BDBM50014828(CHEMBL2368185 | (E)-6-{2-[2,4-Bis-(4-fluoro-phenyl...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 155376BDBM155376(US9006282, Example 2, Compound 4 | US9102656, Exam...)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50042625BDBM50042625((E)-(3R,5S)-7-[2,4-Bis-(4-fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50014820BDBM50014820(CHEMBL2368189 | (E)-6-{2-[2-Cyclohexyl-4-(4-fluoro...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231035BDBM50231035(sodium; (3R,5R)-7-[3-(3-carbamoylmethyl-phenylsulf...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007295BDBM50007295(CHEMBL2367823 | Sodium; 7-[4-(4-fluoro-phenyl)-2,6...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of solubilized HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50014840BDBM50014840(CHEMBL2368197 | (E)-6-{2-[4-(4-Fluoro-phenyl)-2,6-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 155380BDBM155380(US9006282, Example 2, Compound 8 | US9102656, Exam...)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 20711BDBM20711(sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-[(2-phenylp...)
Affinity DataIC50: 6.10nM EC50:  1.10nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50346286BDBM50346286(sodium(3R,5R)-7-(5-cyclopropyl-4-(3-fluorobenzylca...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50346288BDBM50346288(sodium(3R,5R)-7-(5-cyclopropyl-4-(3,4-difluorobenz...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 22155BDBM22155((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methy...)
Affinity DataIC50: 2.5nM EC50:  1.20nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50346282BDBM50346282(sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
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