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TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50558959(CHEMBL4740594)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to human MetAP1 expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50558957(CHEMBL4755128)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human MetAP1 expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50558956(CHEMBL4743733)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to human MetAP1 expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50558967(CHEMBL4759563)
Affinity DataKd:  8.5nMAssay Description:Binding affinity to human MetAP1 expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50375165(CHEMBL271696)
Affinity DataKi:  10nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435210(CHEMBL2392907)
Affinity DataEC50:  36nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433382(CHEMBL1329554)
Affinity DataEC50:  49nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435211(CHEMBL2392906)
Affinity DataEC50:  49nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435184(CHEMBL2392932)
Affinity DataEC50:  63nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433386(CHEMBL2375615)
Affinity DataEC50:  73nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433393(CHEMBL2375622)
Affinity DataEC50:  81nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433373(CHEMBL2375609)
Affinity DataEC50:  93nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435202(CHEMBL2392914)
Affinity DataEC50:  93nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433391(CHEMBL2375620)
Affinity DataEC50:  94nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433387(CHEMBL2375616)
Affinity DataEC50:  94nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433395(CHEMBL2375624)
Affinity DataEC50:  100nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50267199(CHEMBL4079583)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433392(CHEMBL2375621)
Affinity DataEC50:  110nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433381(CHEMBL2375613)
Affinity DataEC50:  110nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433380(CHEMBL2375612)
Affinity DataEC50:  120nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433374(CHEMBL2375610)
Affinity DataEC50:  120nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435207(CHEMBL2392910)
Affinity DataEC50:  140nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435201(CHEMBL2392915)
Affinity DataEC50:  160nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435183(CHEMBL2392933)
Affinity DataEC50:  160nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433389(CHEMBL2375618)
Affinity DataEC50:  180nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433375(GNF-Pf-359 | CHEMBL472879)
Affinity DataEC50:  190nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435182(CHEMBL2392934)
Affinity DataEC50:  200nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435195(CHEMBL2392921)
Affinity DataEC50:  200nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435198(CHEMBL2392918)
Affinity DataEC50:  220nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433399(CHEMBL2375608)
Affinity DataEC50:  250nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435197(CHEMBL2392919)
Affinity DataEC50:  260nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435196(CHEMBL2392920)
Affinity DataEC50:  260nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435212(CHEMBL2392905)
Affinity DataEC50:  270nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433377(CHEMBL2375628)
Affinity DataEC50:  280nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435208(CHEMBL2392909)
Affinity DataEC50:  300nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50042874(2,2'-bipyridine | 2,2'-Bipyridin | 2,2'-bipyridyl ...)
Affinity DataEC50:  320nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435188(CHEMBL2392928)
Affinity DataEC50:  330nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435209(CHEMBL2392908)
Affinity DataEC50:  330nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataEC50:  350nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataEC50:  360nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435227(CHEMBL2392772)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM17589(bestatin-type inhibitor, 4 | CHEMBL352943 | (2S,3R...)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM17589(bestatin-type inhibitor, 4 | CHEMBL352943 | (2S,3R...)
Affinity DataIC50: 370nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435187(CHEMBL2392929)
Affinity DataEC50:  380nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433383(CHEMBL2375614)
Affinity DataEC50:  390nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433398(CHEMBL2375607)
Affinity DataEC50:  390nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433384(CHEMBL45721)
Affinity DataEC50:  410nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50435192(CHEMBL2392924)
Affinity DataEC50:  420nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50433376(CHEMBL2375627)
Affinity DataEC50:  430nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
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