Compile Data Set for Download or QSAR
Report error Found 2535 of affinity data for UniProtKB/TrEMBL: P56718
TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.117nMAssay Description:Antagonist activity at recombinant rat OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM104700(US8569311, 1-10)
Affinity DataKi:  0.710nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM104689(US8569311, A-9)
Affinity DataKi:  1nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM104697(US8569311, 1-1)
Affinity DataKi:  1.80nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314889(US10183953, Example 66 | (3-fluoro-2-(pyrimidin-2-...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314986(US10183953, Example 167 | ((1S,4S,6R)-6-((5-bromop...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314985(US10183953, Example 166 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314987(US10183953, Example 168 | ((1S,4S,6R)-6-((5-bromop...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314629([(1R,2R,4S,5R)-2-deuterio-2-(trideuteriomethyl)-5-...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314653((6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)((...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314889(US10183953, Example 66 | (3-fluoro-2-(pyrimidin-2-...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314986(US10183953, Example 167 | ((1S,4S,6R)-6-((5-bromop...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314987(US10183953, Example 168 | ((1S,4S,6R)-6-((5-bromop...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314985(US10183953, Example 166 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  2nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM104692(US8569311, E-5)
Affinity DataKi:  2.90nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314847((3-methyl-2-(oxazol-2-yl)phenyl)((1S,4R,6R)-6-((5-...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143794(US8969352, 55 | US9611277, Example 55 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314974(US10183953, Example 153 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314965(US10183953, Example 144 | (3-fluoro-2-(2H-1,2,3-tr...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314996(US10183953, Example 177 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143792(US8969352, 53 | US9611277, Example 53 | US10183953...)
Affinity DataKi:  3nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143787(US8969352, 48 | US9611277, Example 48 | US10183953...)
Affinity DataKi:  3nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143792(US8969352, 53 | US9611277, Example 53 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314927(US10183953, Example 106 | ((1S,4R,6R)-6-((5-bromop...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143787(US8969352, 48 | US9611277, Example 48 | US10183953...)
Affinity DataKi:  3nM ΔG°:  -45.2kJ/moleT: 2°CAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM 001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143794(US8969352, 55 | US9611277, Example 55 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314969(US10183953, Example 148 | (2-(pyrimidin-2-yl)pheny...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM315001(US10183953, Example 182 | ((1S,4S,6R)-6-(benzo[d]o...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143792(US8969352, 53 | US9611277, Example 53 | US10183953...)
Affinity DataKi:  3nM ΔG°:  -45.2kJ/moleT: 2°CAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM 001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143787(US8969352, 48 | US9611277, Example 48 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143794(US8969352, 55 | US9611277, Example 55 | US10183953...)
Affinity DataKi:  3nM ΔG°:  -45.2kJ/moleT: 2°CAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM 001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314443((R/S)-(5-fluoro-2-(pyrimidin-2-yl)phenyl)(−3...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314988(US10183953, Example 169 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143794(US8969352, 55 | US9611277, Example 55 | US10183953...)
Affinity DataKi:  3nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143792(US8969352, 53 | US9611277, Example 53 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143771(US8969352, 32 | US10183953, Example 32 | US9845333...)
Affinity DataKi:  3nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143771(US8969352, 32 | US10183953, Example 32 | US9845333...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314996(US10183953, Example 177 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314496(US9611262, Example 63 | (R/S)-(6-methyl-3-(2H-1,2,...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143792(US8969352, 53 | US9611277, Example 53 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143792(US8969352, 53 | US9611277, Example 53 | US10183953...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314617([(1R,2R,4S,5R)-5-[(5-chloro-2-pyridyl)oxy]-2-methy...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM143771(US8969352, 32 | US10183953, Example 32 | US9845333...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314927(US10183953, Example 106 | ((1S,4R,6R)-6-((5-bromop...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314639([2-(6-fluoro-2-pyridyl)phenyl]-[(1R,2R,4S,5R)-2-me...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314974(US10183953, Example 153 | (2-(2H-1,2,3-triazol-2-y...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314969(US10183953, Example 148 | (2-(pyrimidin-2-yl)pheny...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314847((3-methyl-2-(oxazol-2-yl)phenyl)((1S,4R,6R)-6-((5-...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314618([(1R,2R,4S,5R)-5-[(5-chloro-2-pyridyl)oxy]-2-methy...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM314503((3-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)((1S*,3R...)
Affinity DataKi:  3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

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