Compile Data Set for Download or QSAR
Report error Found 248 of affinity data for UniProtKB/TrEMBL: P58154
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50088453(CHEMBL72433 | NS3570, 5 | 1-(6-bromo-5-ethoxypyrid...)
Affinity DataKi:  0.0670nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataKd:  0.0835nMpH: 7.4 T: 2°CAssay Description:Interaction assay using AChBP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataKi:  0.0970nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to freshwater snail Lymnaea stagnalis AChBP assessed as [3H]EPI binding by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)
Affinity DataKd:  0.400nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50320567(3-(2,4-Dihydroxybenzylidene)anabaseine | CHEMBL116...)
Affinity DataKd:  0.800nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50320526(3-(4-Aminobenzylidene)anabaseine | CHEMBL1163383)
Affinity DataKd:  0.800nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520722(CHEMBL4554047)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  1.30nM ΔG°:  -49.9kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50088454(NS3920, 4 | CHEMBL306387 | 1-(6-bromopyridin-3-yl)...)
Affinity DataKi:  1.30nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM91603(4' | alpha7 agonists 4')
Affinity DataKi:  2nM ΔG°:  -48.8kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM92377(NS3573, 2)
Affinity DataKi:  2.20nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520723(CHEMBL4440256)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataKd:  2.67nMpH: 7.4 T: 2°CAssay Description:Interaction assay using AChBP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50088438(CHEMBL71085 | 1-Pyridin-3-yl-[1,4]diazepane | NS35...)
Affinity DataKi:  3.10nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520715(CHEMBL4437999)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520705(CHEMBL4458658)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM91615(15q | alpha7 agonists 15q)
Affinity DataKi:  4nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520710(CHEMBL4551353)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520720(CHEMBL4557873)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520729(CHEMBL4541936)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520732(CHEMBL4444365)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520716(CHEMBL4467323)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM86311(CAS_485-35-8 | NSC_22407 | Cytisine | Cytisine-(-)...)
Affinity DataKi:  8.20nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50088437(CHEMBL303889 | NS3570, 3 | 1-(5-Phenyl-pyridin-3-y...)
Affinity DataKi:  8.90nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520718(CHEMBL4447538)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520727(CHEMBL4537917)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520712(CHEMBL4556242)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520706(CHEMBL4437423)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520719(CHEMBL4452235)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520731(CHEMBL4558905)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM92878(Quinuclidine analogue, 5)
Affinity DataKd:  12.8nMpH: 7.4 T: 2°CAssay Description:Interaction assay using AChBP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50382466(CHEMBL2024087)
Affinity DataKi:  12.8nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520728(CHEMBL4447431)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50393247(CHEMBL1258006)
Affinity DataKi:  14.4nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520713(CHEMBL4444981)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50472282(descyanothiacloprid)
Affinity DataKi:  16nMAssay Description:Binding affinity to freshwater snail Lymnaea stagnalis AChBP assessed as [3H]EPI binding by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520717(CHEMBL4540765)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520711(CHEMBL4579917)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520707(CHEMBL4451952)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50078048(1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-(2Z)-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to freshwater snail Lymnaea stagnalis AChBP assessed as [3H]EPI binding by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50417105(CHEMBL1258240)
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50061564(3-[1-(2,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-3,4,...)
Affinity DataKd:  19nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520721(CHEMBL4448437)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50120210(CHEMBL3616577)
Affinity DataKd:  20nMAssay Description:Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50120210(CHEMBL3616577)
Affinity DataKd:  20nMAssay Description:Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM91613(13q | alpha7 agonists 13q)
Affinity DataKi:  20nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50393247(CHEMBL1258006)
Affinity DataKd:  20nMAssay Description:Binding affinity to Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression system by surface plasmon resonance biosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50382467(CHEMBL2024089)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

LigandPNGBDBM50520730(CHEMBL4537587)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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