Compile Data Set for Download or QSAR
Report error Found 686 for UniProtKB: Q00961
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015743(CHEMBL69034 | Acetic acid 3-[1-(3,6-dihydro-2H-pyr...)
Affinity DataKi:  6nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015738(CHEMBL302321 | 3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-...)
Affinity DataKi:  7nMAssay Description:Ability to displace [3H]TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50111396([[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,...)
Affinity DataKi:  11.6nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015734(CHEMBL307113 | 1-(1-Thiophen-2-yl-cyclohexyl)-1,2,...)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50091629(5-{3-[4-(4-Fluoro-benzyl)-4-hydroxy-piperidin-1-yl...)
Affinity DataIC50: 24nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015741(CHEMBL306450 | 1-[1-(3-Methoxy-phenyl)-cyclohexyl]...)
Affinity DataKi:  33nMAssay Description:Ability to displace [3H]TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Copenhagen

LigandPNGBDBM213888(TK40 | 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]...)
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583031(CHEMBL5081078)
Affinity DataEC50:  36nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015732(CHEMBL71302 | 1-(1-Phenyl-cyclohexyl)-1,2,3,6-tetr...)
Affinity DataKi:  37nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583020(CHEMBL5087374)
Affinity DataEC50:  40nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50280813(5-[(1S,2S)-1-Hydroxy-2-(4-phenyl-piperidin-1-yl)-p...)
Affinity DataIC50: 40nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 55nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015733(CHEMBL71834 | 3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-c...)
Affinity DataKi:  56nMAssay Description:Ability to displace [3H]TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataKi:  60nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583019(CHEMBL5081008)
Affinity DataEC50:  63nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50419775(CHEMBL1950808)
Affinity DataKi:  70nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583032(CHEMBL5090386)
Affinity DataEC50:  74nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015735(CHEMBL307988 | 1-(1-m-Tolyl-cyclohexyl)-1,2,3,6-te...)
Affinity DataKi:  81nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataKi:  91nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015744(CHEMBL414875 | 1-[1-(3-Methoxymethoxy-phenyl)-cycl...)
Affinity DataKi:  92nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164540((2R,3S)-1-(Phenanthrene-2-carbonyl)-piperazine-2,3...)
Affinity DataKi:  96nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50091649(6-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1-meth...)
Affinity DataIC50: 98nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2B NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164549((2R,3S)-1-(7-Bromo-phenanthrene-2-carbonyl)-pipera...)
Affinity DataKi:  99.4nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164549((2R,3S)-1-(7-Bromo-phenanthrene-2-carbonyl)-pipera...)
Affinity DataKi:  100nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 100nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50220152(2-(Amino-carboxy-methyl)-cyclopropanecarboxylic ac...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2C receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583021(CHEMBL5091289)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50280812(5-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 111nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015740(CHEMBL304964 | 1-[1-(3-Vinyl-phenyl)-cyclohexyl]-1...)
Affinity DataKi:  114nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583023(CHEMBL5081203)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50432711(CHEMBL2348224)
Affinity DataEC50:  124nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2C receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50583022(CHEMBL5085583)
Affinity DataEC50:  140nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50018933(CHEMBL44566 | 1-(3-Methyl-1-phenyl-cyclohexyl)-pip...)
Affinity DataKi:  170nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 170nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]L-689,560 at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50440067(CHEMBL2426073 | CHEMBL2426072)
Affinity DataIC50: 200nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50440060(CHEMBL2426081)
Affinity DataIC50: 220nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50280811(5-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 231nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015731(CHEMBL304550 | 1-[1-(3-Methylsulfanyl-phenyl)-cycl...)
Affinity DataKi:  231nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 263nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015736(CHEMBL67637 | 1-[1-(3-Fluoro-phenyl)-cyclohexyl]-1...)
Affinity DataKi:  281nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164555((2R,3S)-1-(9,10-Dihydro-phenanthrene-2-carbonyl)-p...)
Affinity DataKi:  290nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164555((2R,3S)-1-(9,10-Dihydro-phenanthrene-2-carbonyl)-p...)
Affinity DataKi:  290nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50436093(CHEMBL2397268)
Affinity DataEC50:  300nMAssay Description:Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015739(CHEMBL68100 | 3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-c...)
Affinity DataKi:  324nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50238357(CHEMBL4100452)
Affinity DataEC50:  340nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50238363(CHEMBL4099510)
Affinity DataEC50:  350nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50238354(CHEMBL4070902)
Affinity DataEC50:  350nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
Displayed 1 to 50 (of 686 total ) | Next | Last >>
Jump to: