Compile Data Set for Download or QSAR
Report error Found 321 of affinity data for UniProtKB/TrEMBL: Q03111
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to MBP-tagged human recombinant ENL (489 to 559 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606137(CHEMBL5187921)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to MBP-tagged human recombinant ENL (489 to 559 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617558(CHEMBL5400413)
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529556(CHEMBL4552313)
Affinity DataIC50: 14nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737245(US20250136592, Example 78)
Affinity DataIC50: 14nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737208(US20250136592, Example 41)
Affinity DataIC50: 14nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617550(CHEMBL5423431)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737246(US20250136592, Example 79)
Affinity DataIC50: 15nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617561(CHEMBL5438748)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617549(CHEMBL5411777)
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617561(CHEMBL5438748)
Affinity DataKd:  17nMAssay Description:Binding affinity to C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737168(US20250136592, Example 1)
Affinity DataIC50: 17nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617544(CHEMBL5397340)
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737222(US20250136592, Example 55)
Affinity DataIC50: 18nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737232(US20250136592, Example 65)
Affinity DataIC50: 18nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737247(US20250136592, Example 80)
Affinity DataIC50: 18nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529556(CHEMBL4552313)
Affinity DataIC50: 18nMAssay Description:Inhibition of His6-tagged ENL YEATS domain (unknown origin) expressed in Escherichia coli BL21 DE3 and biotinylated H3K27ac peptide interaction using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617551(CHEMBL5427068)
Affinity DataIC50: 19nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617542(CHEMBL5404010)
Affinity DataIC50: 19nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737196(US20250136592, Example 29)
Affinity DataIC50: 21nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617556(CHEMBL5416453)
Affinity DataIC50: 22nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617563(CHEMBL5430847)
Affinity DataIC50: 22nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529556(CHEMBL4552313)
Affinity DataKd:  25nMAssay Description:Binding affinity to C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737219(US20250136592, Example 52)
Affinity DataIC50: 25nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617569(CHEMBL5418436)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal StrepII-SUMO or SUMO-AviTag/Cterminal 6xHis tagged ENL (unknown origin) (1 to 148 residues) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617569(CHEMBL5418436)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant C-terminal 6-His tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21 cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737216(US20250136592, Example 49)
Affinity DataIC50: 26nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737214(US20250136592, Example 47)
Affinity DataIC50: 28nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617548(CHEMBL5400474)
Affinity DataIC50: 28nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737233(US20250136592, Example 66)
Affinity DataIC50: 29nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737215(US20250136592, Example 48)
Affinity DataIC50: 30nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617569(CHEMBL5418436)
Affinity DataKd:  30nMAssay Description:Binding affinity to C-terminal 6-His tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737251(US20250136592, Example 84)
Affinity DataIC50: 31nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617555(CHEMBL5414763)
Affinity DataIC50: 32nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617564(CHEMBL5421344)
Affinity DataIC50: 32nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737207(US20250136592, Example 40)
Affinity DataIC50: 34nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617552(CHEMBL5438461)
Affinity DataIC50: 35nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737235(US20250136592, Example 68)
Affinity DataIC50: 35nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617545(CHEMBL5395585)
Affinity DataIC50: 35nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617543(CHEMBL5429534)
Affinity DataIC50: 37nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737210(US20250136592, Example 43)
Affinity DataIC50: 37nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737220(US20250136592, Example 53)
Affinity DataIC50: 38nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617547(CHEMBL5417838)
Affinity DataIC50: 38nMAssay Description:Inhibition of C-terminal 6xHis-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using bioti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50623091(CHEMBL5437942)
Affinity DataIC50: 40nMAssay Description:Inhibition of 5x6His-tagged ENL YEATS domain (unknown origin) using biotinylated peptide H3K9cr (1 to 20 residues) preincubated for 15 mins followed ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737253(US20250136592, Example 86)
Affinity DataIC50: 41nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737200(US20250136592, Example 33)
Affinity DataIC50: 42nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737206(US20250136592, Example 39)
Affinity DataIC50: 43nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM737203(US20250136592, Example 36)
Affinity DataIC50: 43nMAssay Description:Compounds of the invention were dissolved in DMSO at a concentration of 3 mM with subsequent dilutions in assay buffer (50 mM HEPES PH7.0, 150 mM NaC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50566877(CHEMBL4863719)
Affinity DataKd:  45nMAssay Description:Binding affinity to human His-ENL YEATS domain assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProtein ENL(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50566890(CHEMBL4865432)
Affinity DataKd:  46nMAssay Description:Binding affinity to human His-ENL YEATS domain assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
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