Compile Data Set for Download or QSAR
Report error Found 12 of affinity data for UniProtKB/TrEMBL: Q16186
TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  13nMAssay Description:Binding affinity to human ADRM1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698744(US20240317732, Compound XL5)
Affinity DataKd:  1.48E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698746(US20240317732, Compound XL24)
Affinity DataKd:  1.74E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698750(US20240317732, Compound XL28)
Affinity DataKd:  3.82E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698745(US20240317732, Compound XL23)
Affinity DataKd:  3.88E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698749(US20240317732, Compound XL27)
Affinity DataKd:  3.94E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698747(US20240317732, Compound XL25)
Affinity DataKd:  4.12E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698748(US20240317732, Compound XL26)
Affinity DataKd:  6.67E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  7.09E+3nMAssay Description:Binding affinity to human ADRM1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698751(US20240317732, Compound XL29)
Affinity DataKd:  7.81E+3nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM698752(US20240317732, Compound XL30)
Affinity DataKd:  1.24E+4nMAssay Description:ITC experiments were performed at 25° C. on a MicroCal iTC200 system (Malvern, PA, USA). hRpn13 Pru, XL5, XL5 derivative, or RA190 were prepared in b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetProteasomal ubiquitin receptor ADRM1(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50628987(CHEMBL5418942)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to Rpn-13(unknown origin) pru domain assessed as dissociation constant by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed